Results 291 to 300 of about 526,413 (332)

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Genome Engineering by RNA-Guided Transposition for Anabaena sp. PCC 7120. [PDF]

ACS Synth Biol
Arévalo S, Pérez Rico D, Abarca D, Dijkhuizen LW, Sarasa-Buisan C, Lindblad P, Flores E, Nierzwicki-Bauer S, Schluepmann H.   +8 more
europepmc   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

Development of a Recombineering System for the Acetogen <i>Eubacterium limosum</i> with Cas9 Counterselection for Markerless Genome Engineering. [PDF]

ACS Synth Biol
Sanford PA, Woolston BM.
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Genome Engineering as a Therapeutic Approach in Cancer Therapy: A Comprehensive Review. [PDF]

Adv Genet (Hoboken)
Gemayel J, Chebly A, Kourie H, Hanna C, Mheidly K, Mhanna M, Karam F, Ghoussaini D, Najjar PE, Khalil C.   +9 more
europepmc   +1 more source

CRISPR-aided genome engineering for secondary metabolite biosynthesis in Streptomyces. [PDF]

J Ind Microbiol Biotechnol
Lee Y, Hwang S, Kim W, Kim JH, Palsson BO, Cho BK.   +5 more
europepmc   +1 more source

A noninvasive photoactivatable split-Cre recombinase system for genome engineering in zebrafish. [PDF]

iScience
Elsaid R, Mikdache A, Diabangouaya P, Gros G, Hernández PP.   +4 more
europepmc   +1 more source

HIV-1 Proviral Genome Engineering with CRISPR-Cas9 for Mechanistic Studies. [PDF]

Viruses
Hyder U, Shukla A, Challa A, D'Orso I.
europepmc   +1 more source

Editorial: Advances and challenges of genome engineering tools in healthcare: molecular insights into CRISPR/Cas technology. [PDF]

Front Mol Biosci
Kumar S, Venkat S.
europepmc   +1 more source