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Mining proteases in the genome databases
Essays in Biochemistry, 2002Protease data mining can take advantage both of the many specialist, Web-available databases that cover the genetic, protein and nucleic acid sequence information that is specific to a variety of organisms, and of a flexible, but defined, classification system. However, precomputed data, such as gene predictions, should be used with care.
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ACS Synthetic Biology, 2020
In vivo biosensors are powerful tools for metabolic engineering and synthetic biology applications. However, development of biosensors is hindered by the limited number of characterized transcriptional regulators.
Huihua Sun, Huimin Zhao, E. Ang
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In vivo biosensors are powerful tools for metabolic engineering and synthetic biology applications. However, development of biosensors is hindered by the limited number of characterized transcriptional regulators.
Huihua Sun, Huimin Zhao, E. Ang
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Genome mining as a biotechnological tool for the discovery of novel marine natural products
Critical Reviews in Biotechnology, 2020Compared to terrestrial environments, the oceans harbor a variety of environments, creating higher biodiversity, which gives marine natural products a high occurrence of significant biology and novel chemistry.
Leixia Chu +4 more
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ACS Chemical Biology, 2020
Phosphonic acid natural products have potent inhibitory activities that have led to their application as antibiotics. Recent studies uncovered large collections of gene clusters encoding for unknown phosphonic acids across microbial genomes. However, our
Chase M Kayrouz +3 more
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Phosphonic acid natural products have potent inhibitory activities that have led to their application as antibiotics. Recent studies uncovered large collections of gene clusters encoding for unknown phosphonic acids across microbial genomes. However, our
Chase M Kayrouz +3 more
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Resources for mining mollicute genomes
2005Nombre de pages de l'ouvrage: XII-604 p.
Barre, A +3 more
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Mining information for functional genomics
IEEE Intelligent Systems, 2002Bernardi, Ratsch, Kania. Saric and Rojas discuss interdisciplinary work as the key to functional genomics. Park discusses network biology (data mining of biological networks). Schatz discusses the construction of analysis environments beyond the genome and the Web.
B.R. Schatz +9 more
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2006
The genomic data mine represents a fundamental shift from genetics to genomics, essentially from the study of one gene at a time to the study of entire genetic metabolic networks and whole genomes. Experimental laboratory data are deposited into large public repositories and a wealth of computational data mining algorithms and tools are applied to mine
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The genomic data mine represents a fundamental shift from genetics to genomics, essentially from the study of one gene at a time to the study of entire genetic metabolic networks and whole genomes. Experimental laboratory data are deposited into large public repositories and a wealth of computational data mining algorithms and tools are applied to mine
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Zeitschrift für Induktive Abstammungs- und Vererbungslehre, 2022
S. Iqbal +7 more
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S. Iqbal +7 more
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Data mining in genome annotation [PDF]
, 2008 Systematic annotation of protein sequences was initiated more than two decades ago by two groups of enthusiasts at the Swiss-Prot (Bairoch and Boeckmann 1991) and PIR (George et al. 1986) databases and is actively continuing today as a centralized UniProt effort (see Chap. 10 in this volume).
Dmitrij Frishman +2 more
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Mining genomes and ‘metagenomes’ for novel catalysts
Current Opinion in Biotechnology, 2005Advances in the field of genomics and 'metagenomics' have dramatically revised our view of microbial biodiversity and its potential for biotechnological applications. Considering the estimation that >99% of microorganisms in most environments are not amenable to culturing, very little is known about their genomes, genes and encoded enzymatic activities.
Manuel Ferrer +2 more
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