Results 91 to 100 of about 3,886,811 (311)
Principles of the 3D genome organization in malaria mosquitoes
, 2020 Poster "Principles of the 3D genome organization in malaria mosquitoes.
Varvara Lukyanchikova (8713636) +6 more
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
On the evolution of chromosomal regions with high gene strand bias in bacteria
mBioOn circular bacterial chromosomes, the majority of genes are coded on the leading strand. This gene strand bias (GSB) ranges from up to 85% in some Bacillota to a little more than 50% in other phyla.
Jürgen Tomasch +4 more
doaj +1 more source
Genome-wide identification and organization of seed storage protein genes of Cannabis sativa
Biologia Plantarum, 2018 Hemp (Cannabis sativa L.) seeds have been recognized as a nutritional protein source for humans and animals. In this study, gene families encoding precursor polypeptides of three storage protein classes, including six 11S edestin, two 2S albumin and one ...
E. Ponzoni, I. M. Brambilla, I. Galasso
doaj +1 more source
Genome organization of DNA replication timing and its link to chromatin and transcription [PDF]
, 2008 The replication of the genome is a highly organized process. Not every sequence replicates at the same time, instead some genes replicate early, while others replicate later during S phase.
Schwaiger, Michaela
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Observing copepods through a genomic lens
Frontiers in Zoology, 2011 Background Copepods outnumber every other multicellular animal group. They are critical components of the world's freshwater and marine ecosystems, sensitive indicators of local and global climate change, key ecosystem service providers, parasites and ...
Johnson Stewart C +5 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Leveraging the Assembly of the Durum Wheat Genome cv. Svevo
, 2017 Tetraploid wheat species, with his two wild and cultivated subspecies T. turgidum ssp. dicoccoides and ssp. durum, is a cornerstone of the wheat polyploidy complex.
The International Durum Wheat Sequencing Consortium +3 more
core +1 more source
, 2022 The human genome is a complex design of life, composed of billions of base pairs intricately organized within our cells. It is not just a simple sequence of DNA, but a sophisticated structure packed with layers of information that guide every cellular process.
openaire +1 more source