Results 71 to 80 of about 3,886,811 (311)

Gene organization of the mitochondrial genome.

open access: yes, 2015
Gene organization of the mitochondrial genome.
Li Fan (170266)   +5 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

GENOME ORGANIZATION AND GEOGRAPHICAL DISTRIBUTION OF THE NATURAL INTERGENOTYPIC RECOMBINANT OF HEPATITIS C VIRUS RF1_2k/1b

open access: yesИнфекция и иммунитет, 2014
. For many years, the viral hepatitis C is considered as one of the most actual infectious pathologies of human. During the last decade the number of registered cases of chronic viral hepatitis C in Russia increased two times and reached 40.9‰. According
O. V. Kalinina
doaj   +1 more source

Rice Genome Organization: the Centromere and Genome Interactions [PDF]

open access: yesAnnals of Botany, 2002
Over the last decade, many varied resources have become available for genome studies in rice. These resources include over 4000 DNA markers, several bacterial artificial chromosome (BAC) libraries, P-1 derived artificial chromosome (PAC) libraries and yeast artificial chromosome (YAC) libraries (genomic DNA clones, filters and end-sequences ...
Nori, Kurata   +2 more
openaire   +2 more sources

Organization of the Cyprus mouflon mitochondrial genome.

open access: yes, 2015
Organization of the Cyprus mouflon mitochondrial genome.
Salvatore Naitana (182803)   +12 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Systemic delivery of engineered compact AsCas12f by a positive-strand RNA virus vector enables highly efficient targeted mutagenesis in plants

open access: yesFrontiers in Plant Science
Because virus vectors can spread systemically autonomously, they are powerful vehicles with which to deliver genome-editing tools into plant cells. Indeed, a vector based on a positive-strand RNA virus, potato virus X (PVX), harboring SpCas9 and its ...
Kazuhiro Ishibashi   +9 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Analysis of expressed sequence tags (ESTs) from cat cerebrum and cerebellum cDNA librariesv

open access: yes, 2005
The cat is an attractive candidate for an animal model for human disease, genome evolution, comparative research for several reasons. Although mouse and rat have been powerful models to examine molecular mechanisms of human hereditary disorders.
N. Yhuki, 김충곤, S. Obrien
core   +1 more source

Gene location and DNA density determine transcription factor distributions in Escherichia coli

open access: yesMolecular Systems Biology, 2012
The diffusion coefficient of the transcription factor LacI within living Escherichia coli has been measured directly by in vivo tracking to be D=0.4 μm2/s. At this rate, simple models of diffusion lead to the expectation that LacI and other proteins will
Thomas E Kuhlman, Edward C Cox
doaj   +1 more source

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