Results 51 to 60 of about 5,189,630 (339)
Cells, 2022 Formerly hailed as “undruggable” proteins, transcription factors (TFs) are now under investigation for targeted therapy. In cancer, this may alter, inter alia, immune evasion or replicative immortality, which are implicated in genome organization, a ...
Damian Kołat +4 more
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Joint assembly and genetic mapping of the Atlantic horseshoe crab genome reveals ancient whole genome duplication [PDF]
, 2013 Horseshoe crabs are marine arthropods with a fossil record extending back approximately 450 million years. They exhibit remarkable morphological stability over their long evolutionary history, retaining a number of ancestral arthropod traits, and are ...
Brockmann, H Jane +6 more
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Evolution and Genetic Diversity of Primate Cytomegaloviruses
Microorganisms, 2020 Cytomegaloviruses (CMVs) infect many mammals, including humans and non–human primates (NHPs). Human cytomegalovirus (HCMV) is an important opportunistic pathogen among immunocompromised patients and represents the most common infectious cause of birth ...
Rachele Cagliani +3 more
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Genome restructuring in mouse embryos during reprogramming and early development [PDF]
, 1996 Although a growing number of studies investigates functional genome organization in somatic cell nuclei, it is largely unknown how mammalian genome organization is established during embryogenesis.
Martin, Catherine +5 more
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Genome organization: experiments and modeling [PDF]
Chromosome Research, 2017 7 pages, 1 ...
Gilbert, Nick, Marenduzzo, Davide
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Gene silencing and large-scale domain structure of the E. coli genome
, 2012 The H-NS chromosome-organizing protein in E. coli can stabilize genomic DNA loops, and form oligomeric structures connected to repression of gene expression.
Lagomarsino, Marco Cosentino +2 more
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Genome reorganization in different cancer types: detection of cancer specific breakpoint regions [PDF]
, 2019 Background: Tumorigenesis is a multi-step process which is accompanied by substantial changes in genome organization. The development of these changes is not only a random process, but rather comprise specific DNA regions that are prone to the ...
Klein, Andreas +3 more
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Dynamic bacterial genome organization [PDF]
Molecular Microbiology, 1997 Recently completed projects of sequencing chromosomal fragments and entire chromosomes, as well as physical mapping of genomes, have opened novel inroads to the understanding of the biology of bacterial genomes. From these studies one may draw some conclusions.
openaire +2 more sources
Radial Organization in the Mammalian Nucleus
Frontiers in Genetics, 2020 In eukaryotic cells, most of the genetic material is contained within a highly specialized organelle—the nucleus. A large body of evidence indicates that, within the nucleus, chromatinized DNA is spatially organized at multiple length scales.
Nicola Crosetto, Magda Bienko
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BIOPHYSICAL BASES OF GENOME ORGANIZATION
Наука и инновации в медицине, 2017 Aim - the analysis of nucleotide sequences of DNA molecules and the bases of the information storage with the help of DNA. Material and methods - the study is based on Markov chain theory and Bayesian Information Criterion. Results. Principles of genetic
AN N Volobuev +2 more
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