Results 51 to 60 of about 3,886,811 (311)
Self-organization in the genome [PDF]
Proceedings of the National Academy of Sciences, 2009 One of the most important recent discoveries in the field of genome biology has been the demonstration that genomes are nonrandomly organized in the cell nucleus (1, 2). Examples now abound of chromosomes or genes localizing to a particular location in the nucleus or undergoing positional changes as they became activated or repressed.
openaire +2 more sources
Genome-wide analysis of local chromatin packing in Arabidopsis thaliana
, 2019 Hi-C maps (2 kb bin: chromosomal; 20 kb bin: genome-wide) of Arabidopsis thaliana (Col-0).These Hi-C maps were used for analyzing chromatin organization patterns presented in:Congmao Wang, Chang Liu, Damian Roqueiro, Dominik Grimm, Rebecca Schwab, Claude
Chang Liu (6570488)
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A fragmented metazoan organellar genome [PDF]
, 2008 Background: Animal mitochondrial (mt) genomes are characteristically circular molecules of ~16–20 kb. Medusozoa (Cnidaria excluding Anthozoa) are exceptional in that their mt genomes are linear and sometimes subdivided into two to presumably four ...
Wörheide, Gert +2 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
copA cluster presence and genome organization across genera.
, 2021 copA cluster presence and genome organization across genera.
Pratima Gautam (11495569) +6 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
HiCeekR: A Novel Shiny App for Hi-C Data Analysis
Frontiers in Genetics, 2019 The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next Generation Sequencing technologies with chromosome conformation capture approach to study the 3D chromatin organization at the genome-wide scale. Although
Lucio Di Filippo +5 more
doaj +1 more source
Mitochondrial DNA. Part B. Resources, 2020 The mitochondrial genome has proven to be a highly successful resource for the investigation of evolution and population genetics. Here, we present the complete mitochondrial genome of Fejervarya multistriata.
Lichun Jiang +5 more
doaj +1 more source
Echinoderes svetlanae genome organization.
, 2016 Echinoderes svetlanae genome organization.
Olga S. Kedrova (3226869) +9 more
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Allele-specific control of replication timing and genome organization during development [PDF]
, 2018 DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional activity and 3D genome organization.
Dimond, AM +20 more
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