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Human Body Single-Cell Atlas of 3D Genome Organization and DNA Methylation

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Zhou J   +28 more
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Organization of the pE194 genome

Molecular and General Genetics MGG, 1980
pE194 is a 3.5 kilobase erythromycin resistance plasmid which was originally isolated from Staphylococcus aureus and has been introduced into Bacillus subtilis. This plasmid specifies at least five polypeptides, detectable in minicell extracts, one of which (E3) is inducible by erythromycin and is required for the expression of erythromycin resistance.
A G, Shivakumar   +3 more
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Genome Organization in Pseudomonas

Annual Review of Microbiology, 1986
INTRODUC][10N .. . . . . . . . . ..... ... . .. ...... . . . . . . . . . . .. . . . . . . . . . . . . . . . .... ...... . . . . . . . . . . .. ... . . . . . . 79 GENETI C ANALY SI S OF PSEUDOMONAS SPECIES . . . . . . . . ... .. ... . . . . .. . . .. . .. ......... 8 1 Genetic Exchange Mechanisms i n Pseudomonas . .. ... .. .. .. . . . .... ... . ... .
B W, Holloway, A F, Morgan
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Organization of the IBV Genome

1984
We have investigated how the information contained within the large RNA genome of IBV is expressed. We began by examining the structure of IBV-specified RNAs. Infected chicken embryo kidney (CEK) cells contain at least 6 IBV RNA species. These consist of the viral genome, RNA F, with an estimated complexity of 23 kb1, and subgenomic RNAs A, B, C, D ...
D F, Stern, B, Sefton
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Circadian organization of the genome

Science, 2018
The clock protein Rev-erbα regulates genome folding to establish circadian gene ...
Carolina Diettrich, Mallet de Lima   +1 more
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Spatial genome organization

Experimental Cell Research, 2004
The linear sequence of genomes exists within the three-dimensional space of the cell nucleus. The spatial arrangement of genes and chromosomes within the interphase nucleus is nonrandom and gives rise to specific patterns. While recent work has begun to describe some of the positioning patterns of chromosomes and gene loci, the structural constraints ...
Luis A, Parada   +2 more
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Retroelements in Genome Organization

Science, 1996
Transposons, mobile pieces of DNA, were first described in maize by B. McClintock. Now maize yields another surprise, as shown by SanMiguel et al . ( p. 765 ) in this week's issue. One particular class of transposon, retrotransposons, is present in the maize genome in numbers so vast that it ...
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Organization of the human genome

Journal of Inherited Metabolic Disease, 1994
SummaryThe human genome contains about 3×109 base pairs which, based on average estimates for the size of coding regions, might suggest an upper limit of about 3 million genes. Evidence from a variety of approaches indicates a much lower figure — in the range 40 000–100 000 genes.
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Human genome organization

Current Opinion in Genetics & Development, 1995
Recent advances have been made in addressing three intriguing aspects of human genome organization: the organization of protein-coding sequences within chromosomes, the structural basis of the metaphase chromosomal banding pattern, and the function of non protein coding DNA.
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Genome organization in prokaryotes

Current Opinion in Genetics & Development, 1993
Most of the well-characterized prokaryotic genomes consist of double-stranded DNA organized as a single circular chromosome 0.6-10 Mb in length and one or more circular plasmid species of 2 kb-1.7 Mb. The past few years, however, have revealed some major variations in genome organization.
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