Results 291 to 300 of about 5,189,630 (339)
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Regulation of genome organization and gene expression by nuclear mechanotransduction
Nature Reviews Molecular Cell Biology, 2017Caroline Uhler, G. Shivashankar
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Experimental Cell Research, 2004
The linear sequence of genomes exists within the three-dimensional space of the cell nucleus. The spatial arrangement of genes and chromosomes within the interphase nucleus is nonrandom and gives rise to specific patterns. While recent work has begun to describe some of the positioning patterns of chromosomes and gene loci, the structural constraints ...
Luis A, Parada +2 more
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The linear sequence of genomes exists within the three-dimensional space of the cell nucleus. The spatial arrangement of genes and chromosomes within the interphase nucleus is nonrandom and gives rise to specific patterns. While recent work has begun to describe some of the positioning patterns of chromosomes and gene loci, the structural constraints ...
Luis A, Parada +2 more
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2022
The human genome is a complex design of life, composed of billions of base pairs intricately organized within our cells. It is not just a simple sequence of DNA, but a sophisticated structure packed with layers of information that guide every cellular process.
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The human genome is a complex design of life, composed of billions of base pairs intricately organized within our cells. It is not just a simple sequence of DNA, but a sophisticated structure packed with layers of information that guide every cellular process.
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Genome Organization in Pseudomonas
Annual Review of Microbiology, 1986INTRODUC][10N .. . . . . . . . . ..... ... . .. ...... . . . . . . . . . . .. . . . . . . . . . . . . . . . .... ...... . . . . . . . . . . .. ... . . . . . . 79 GENETI C ANALY SI S OF PSEUDOMONAS SPECIES . . . . . . . . ... .. ... . . . . .. . . .. . .. ......... 8 1 Genetic Exchange Mechanisms i n Pseudomonas . .. ... .. .. .. . . . .... ... . ... .
B W, Holloway, A F, Morgan
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Current Opinion in Genetics & Development, 1995
Recent advances have been made in addressing three intriguing aspects of human genome organization: the organization of protein-coding sequences within chromosomes, the structural basis of the metaphase chromosomal banding pattern, and the function of non protein coding DNA.
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Recent advances have been made in addressing three intriguing aspects of human genome organization: the organization of protein-coding sequences within chromosomes, the structural basis of the metaphase chromosomal banding pattern, and the function of non protein coding DNA.
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Retroelements in Genome Organization
Science, 1996Transposons, mobile pieces of DNA, were first described in maize by B. McClintock. Now maize yields another surprise, as shown by SanMiguel et al . ( p. 765 ) in this week's issue. One particular class of transposon, retrotransposons, is present in the maize genome in numbers so vast that it ...
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Genome organization in prokaryotes
Current Opinion in Genetics & Development, 1993Most of the well-characterized prokaryotic genomes consist of double-stranded DNA organized as a single circular chromosome 0.6-10 Mb in length and one or more circular plasmid species of 2 kb-1.7 Mb. The past few years, however, have revealed some major variations in genome organization.
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Organization of the pE194 genome
Molecular and General Genetics MGG, 1980pE194 is a 3.5 kilobase erythromycin resistance plasmid which was originally isolated from Staphylococcus aureus and has been introduced into Bacillus subtilis. This plasmid specifies at least five polypeptides, detectable in minicell extracts, one of which (E3) is inducible by erythromycin and is required for the expression of erythromycin resistance.
A G, Shivakumar +3 more
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CTCF: a Swiss-army knife for genome organization and transcription regulation.
Essays in Biochemistry, 2019Orchestrating vertebrate genomes require a complex interplay between the linear composition of the genome and its 3D organization inside the nucleus. This requires the function of specialized proteins, able to tune various aspects of genome organization ...
L. Braccioli, E. de Wit
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Domain organization of eukaryotic genome
Cell Biology International Reports, 1992INTRODUCTION It is a well-established fact that transcription of eukaryotic genes is regulated at several levels. One of these levels is represented by mechanisms that operate within relatively large genomic domains. Active domains are preferentially sensitive to DNase I (for review see Gross and Garrard, 1988). They could be several dozens kb long and
S V, Razin, Y S, Vassetzky
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