Results 11 to 20 of about 1,168,334 (239)

The Chlamydomonas genome project: A decade on [PDF]

open access: yesTrends in Plant Science, 2014
The green alga Chlamydomonas reinhardtii is a popular unicellular organism for studying photosynthesis, cilia biogenesis, and micronutrient homeostasis.
Aksoy, M   +19 more
core   +8 more sources

Genome Projects and the Functional-Genomic Era [PDF]

open access: yesCombinatorial Chemistry & High Throughput Screening, 2005
The problems we face today in public health as a result of the -- fortunately -- increasing age of people and the requirements of developing countries create an urgent need for new and innovative approaches in medicine and in agronomics. Genomic and functional genomic approaches have a great potential to at least partially solve these problems in the ...
Sauer, S., Konthur, Z., Lehrach, H.
openaire   +3 more sources

Medaka genome project [PDF]

open access: yesBriefings in Functional Genomics and Proteomics, 2008
The medaka Oryzias latipes is a small egg-laying freshwater teleost, and has become an excellent model system for ecotoxicology, developmental genetics, genomics and evolutionary biology studies. A high-quality draft genome sequence (700 Mb) of the medaka inbred strain, Hd-rR, has now been completed. In this review, we present an overview of the medaka
Daisuke, Kobayashi, Hiroyuki, Takeda
openaire   +2 more sources

Analysis of SARS-CoV-2 genomic epidemiology reveals disease transmission coupled to variant emergence and allelic variation

open access: yesScientific Reports, 2021
The spread of SARS-CoV-2 created a pandemic crisis with > 150,000 cumulative cases in > 65 countries within a few months. The reproductive number (R) is a metric to estimate the transmission of a pathogen during an outbreak.
D J Darwin R. Bandoy, Bart C. Weimer
doaj   +1 more source

Molecular tools to monitor health and disease – and lucky coincidences

open access: yesUpsala Journal of Medical Sciences, 2022
Improved methods for molecular analyses are obviously central for medical research. I will describe herein our work developing tools to reveal molecular states in health and disease.
Ulf Landegren
doaj   +1 more source

Deciphering Signatures of Mutational Processes Operative in Human Cancer

open access: yesCell Reports, 2013
The genome of a cancer cell carries somatic mutations that are the cumulative consequences of the DNA damage and repair processes operative during the cellular lineage between the fertilized egg and the cancer cell. Remarkably, these mutational processes
Ludmil B. Alexandrov   +4 more
doaj   +1 more source

Mutational signatures of ionizing radiation in second malignancies

open access: yesNature Communications, 2016
Ionizing radiation may induce irreparable DNA damage leading to cancer. Here, the authors identify a specific signature of mutations arising in patients exposed to ionizing radiation and suggest that radiation-induced tumorigenesis is associated with ...
Sam Behjati   +32 more
doaj   +1 more source

Analyses of publicly available Hungatella hathewayi genomes revealed genetic distances indicating they belong to more than one species

open access: yesVirulence, 2021
Hungatella hathewayi has been observed to be a member of the gut microbiome. Unfortunately, little is known about this organism in spite of being associated with human fatalities; it is important to understand virulence mechanisms and epidemiological ...
Laura E. Hernández-Juárez   +7 more
doaj   +1 more source

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