Nature Communications, 2017 Osteosarcoma is a primary malignancy of bone that affects children and adults. Here, the authors sequence childhood and adult osteosarcomas, identifying mutations in insulin-like growth factor signalling genes and distinct genomic rearrangement profiles ...
Sam Behjati +32 more
doaj +1 more source
Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
Cell Reports, 2016 Disordered transcriptomes of cancer encompass direct effects of somatic mutation on transcription, coordinated secondary pathway alterations, and increased transcriptional noise.
Adam Shlien +36 more
doaj +1 more source
Draft Genome Sequences of 1,183 Salmonella Strains from the 100K Pathogen Genome Project. [PDF]
, 2017 Salmonella is a common food-associated bacterium that has substantial impact on worldwide human health and the global economy. This is the public release of 1,183 Salmonella draft genome sequences as part of the 100K Pathogen Genome Project.
Arabyan, Narine +14 more
core +1 more source
Systematic image‐driven analysis of the spatial Drosophila embryonic expression landscape
Molecular Systems Biology, 2010 Discovery of temporal and spatial patterns of gene expression is essential for understanding the regulatory networks and development in multicellular organisms.
Erwin Frise +2 more
doaj +1 more source
Draft Genome Sequence of Multidrug-Resistant Abortive Campylobacter jejuni from Northern California. [PDF]
, 2017 Campylobacter jejuni is an enteric bacterium that can cause abortion in livestock. This is the release of a multidrug-resistant Campylobacter jejuni genome from an isolate that caused an abortion in a cow in northern California.
Clothier, Kristin A +4 more
core +2 more sources
The driver landscape of sporadic chordoma
Nature Communications, 2017 Chordoma is a rare often incurable malignant bone tumour. Here, the authors investigate driver mutations of sporadic chordoma in 104 cases, revealing duplications in notochordal transcription factor brachyury (T), PI3K signalling mutations, and mutations
Patrick S. Tarpey +31 more
doaj +1 more source
Salmonella enhances osteogenic differentiation in adipose-derived mesenchymal stem cells
Frontiers in Cell and Developmental Biology, 2023 The potential of mesenchymal stem cells (MSCs) for tissue repair and regeneration has garnered great attention. While MSCs are likely to interact with microbes at sites of tissue damage and inflammation, like in the gastrointestinal system, the ...
Nuradilla Mohamad-Fauzi +12 more
doaj +1 more source
Draft Genome Sequences of Campylobacter jejuni Strains That Cause Abortion in Livestock. [PDF]
, 2016 Campylobacter jejuni is an intestinal bacterium that can cause abortion in livestock. This publication announces the public release of 15 Campylobacter jejuni genome sequences from isolates linked to abortion in livestock.
Clothier, Kristin A +4 more
core +2 more sources
The Cancer Genome Anatomy Project: EST Sequencing and the Genetics of Cancer Progression
Neoplasia: An International Journal for Oncology Research, 1999 As the process of tumor progression proceeds from the normal cellular state to a preneoplastic condition and finally to the fully invasive form, the molecular characteristics of the cell change as well. These characteristics can be considered a molecular
David B. Krizman +4 more
doaj +1 more source
100K Pathogen Genome Project: 306 Listeria Draft Genome Sequences for Food Safety and Public Health. [PDF]
, 2017 Listeria monocytogenes is a food-associated bacterium that is responsible for food-related illnesses worldwide. This is the initial public release of 306 L. monocytogenes genome sequences as part of the 100K Pathogen Genome Project.
Arabyan, Narine +9 more
core +2 more sources