Results 1 to 10 of about 539,554 (211)

The Human Genome Project, and recent advances in personalized genomics [PDF]

open access: yesRisk Management and Healthcare Policy, 2015
Brenda J Wilson, Stuart G Nicholls Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada Abstract: The language of “personalized medicine” and “personal genomics” has now
Wilson BJ, Nicholls SG
doaj   +2 more sources

The impact of the human genome project on complex disease. [PDF]

open access: yesGenes (Basel), 2014
Bailey JN, Pericak-Vance MA, Haines JL.
europepmc   +2 more sources

The international Human Genome Project (HGP) and China’s contribution [PDF]

open access: yesProtein & Cell, 2017
Xiaoling Wang   +3 more
doaj   +2 more sources

Factors that influence a patient’s decision to engage in genetic research

open access: yesFrontiers in Public Health, 2023
IntroductionThe most challenging step in clinical research studies is patient recruitment. Many research studies do not reach their targets because of participant rejection.
Amal Almutairi   +10 more
doaj   +1 more source

Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background Fetal hemoglobin (HbF) induction has shown promise for the treatment of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective hematopoiesis and thus terminate transfusion dependency for formerly transfusion dependant ...
Noha Hamdy Eltaweel   +4 more
doaj   +1 more source

Genome-wide copy number variation analysis of hepatitis B infection in a Japanese population

open access: yesHuman Genome Variation, 2021
Hepatitis B: Gene copy numbers associated with risk of infection The risk of contracting the hepatitis B virus may be linked to the number of copies of certain genes in an individual’s genome.
Masataka Kikuchi   +7 more
doaj   +1 more source

Narcolepsy type I-associated DNA methylation and gene expression changes in the human leukocyte antigen region

open access: yesScientific Reports, 2023
Narcolepsy type 1 (NT1) is caused by a loss of hypothalamic orexin-producing cells, and autoreactive CD4+ and CD8+ T cells have been suggested to play a role in the autoimmune mechanism.
Kugui Yoshida-Tanaka   +6 more
doaj   +1 more source

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