Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples. [PDF]
PLoS Computational Biology, 2013 There are 10× more bacterial cells in our bodies from the microbiome than human cells. Viral DNA is known to integrate in the human genome, but the integration of bacterial DNA has not been described. Using publicly available sequence data from the human
David R Riley +6 more
doaj +1 more source
Genomics as an Unfinished Science
Cahiers Droit, Sciences & Technologies, 2019 This paper argues that genomics both before and after the Human Genome Project, from 1990 to the present day is defined by its incompleteness, its iteration and should be framed as a question-generating conceptual and technological exercise.
Christopher Donohue
doaj +1 more source
The Human Genome Organisation (HUGO) and a vision for Ecogenomics: the Ecological Genome Project
Human Genomics, 2023 Background The following outlines ethical reasons for widening the Human Genome Organisation’s (HUGO) mandate to include ecological genomics. Main The environment influences an organism’s genome through ambient factors in the biosphere (e.g.
Benjamin Capps +8 more
doaj +1 more source
The Human Genome Project and the Downside of Federal Technology Transfer [PDF]
, 1994 Mr. Harnett argues that emphasizing technology transfer at institutions such as the National Institutes of Health will interfere with what should be regarded as their primary mission, basic ...
Harnett, Christopher J.
core +2 more sources
Human genetics and genomics a decade after the release of the draft sequence of the human genome
Human Genomics, 2011 Substantial progress has been made in human genetics and genomics research over the past ten years since the publication of the draft sequence of the human genome in 2001.
Naidoo Nasheen +4 more
doaj +1 more source
Mining the Common Heritage of Our DNA: Lessons Learned From Grotius and Pardo [PDF]
, 2006 The Human Genome Project generated oceans of DNA sequence data and spurred a multinational race to grab the bounties of these oceans. In response to these DNA property grabs, UNESCO, drawing upon international law precedents addressing analogous grabs in
Bovenberg, Jasper A.
core +1 more source
Towards Better Understanding of Artifacts in Variant Calling from High-Coverage Samples [PDF]
, 2015 Motivation: Whole-genome high-coverage sequencing has been widely used for personal and cancer genomics as well as in various research areas. However, in the lack of an unbiased whole-genome truth set, the global error rate of variant calls and the ...
Li, Heng
core +1 more source
Scaffolder - Software for Reproducible Genome Scaffolding. [PDF]
, 2011 Background: Assembly of short-read sequencing data can result in a fragmented non-contiguous series of genomic sequences. Therefore a common step in a genome project is to join neighboring sequence regions together and fill gaps in the assembly using ...
Hazel A. Barton, Michael D. Barton
core +1 more source
Artificial and Natural Genetic Information Processing [PDF]
, 2017 Conventional methods of genetic engineering and more recent genome editing techniques focus on identifying genetic target sequences for manipulation.
Witzany, Guenther
core
DNA methylation profiling of the human major histocompatibility complex: A pilot study for the Human Epigenome Project [PDF]
, 2004 The Human Epigenome Project aims to identify, catalogue, and interpret genome-wide DNA methylation phenomena. Occurring naturally on cytosine bases at cytosine-guanine dinucleotides, DNA methylation is intimately involved in diverse biological processes ...
Andrews, TD +13 more
core