Results 21 to 30 of about 5,973,095 (357)

Initiation of the Primate Genome Project. [PDF]

open access: yesZool Res, 2022
This work was supported by the National Natural Science Foundation of China (31822048) and Strategic Priority Research Program of the Chinese Academy of Sciences (XDPB17)
Wu DD   +13 more
europepmc   +9 more sources

The Human Genome Project [PDF]

open access: bronzeIUBMB Life, 2001
Francis S. Collins, Monique K. Mansoura
openalex   +5 more sources

Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background Fetal hemoglobin (HbF) induction has shown promise for the treatment of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective hematopoiesis and thus terminate transfusion dependency for formerly transfusion dependant ...
Noha Hamdy Eltaweel   +4 more
doaj   +1 more source

Characterization of tumor-associated reactive astrocytes in gliomas by single-cell and bulk tumor sequencing

open access: yesFrontiers in Neurology, 2023
ObjectiveAstrocytes constitute approximately 30% of cells in gliomas and play important roles in synapse construction and survival. Recently, JAK/STAT pathway activation associated with a new type of astrocyte was reported.
Chuan-bao Zhang   +9 more
doaj   +1 more source

The Feline Genome Project [PDF]

open access: yesAnnual Review of Genetics, 2002
▪ Abstract  The compilation of a dense gene map and eventually a whole genome sequence (WGS) of the domestic cat holds considerable value for human genome annotation, for veterinary medicine, and for insight into the evolution of genome organization among mammals.
O'Brien, Stephen J.   +3 more
openaire   +4 more sources

Towards the Physical Map of the Trypanosoma cruzi Nuclear Genome: Construction of YAC and BAC Libraries of the Reference Clone T. cruzi CL-Brener [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 1997
Strategies to construct the physical map of the Trypanosoma cruzi nuclear genome have to capitalize on three main advantages of the parasite genome, namely (a) its small size, (b) the fact that all chromosomes can be defined, and many of them can be ...
I Ferrari   +31 more
doaj   +1 more source

Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines

open access: yesScientific Reports, 2021
Hepatitis B (HB) vaccines (Heptavax-II and Bimmugen) designed based on HBV genotypes A and C are mainly used for vaccination against HB in Japan. To determine whether there are differences in the genetic background associated with vaccine responsiveness,
Nao Nishida   +23 more
doaj   +1 more source

Genome Projects and the Functional-Genomic Era [PDF]

open access: yesCombinatorial Chemistry & High Throughput Screening, 2005
The problems we face today in public health as a result of the -- fortunately -- increasing age of people and the requirements of developing countries create an urgent need for new and innovative approaches in medicine and in agronomics. Genomic and functional genomic approaches have a great potential to at least partially solve these problems in the ...
Sauer, S., Konthur, Z., Lehrach, H.
openaire   +4 more sources

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