Results 51 to 60 of about 1,119,935 (184)

Genome sequencing project has begun on two plant trypanosomatids (Phytomonas) [PDF]

, 2010
Some trypanosomatids are responsible for wilt in tropical crops, such as hartrot disease in the coconut palm. They have a major economic impact in Latin America and the Caribbean.
Artiguenave, Françoise, Aury, Jean-Marc, Couloux, Arnaud, Da Silva, Corinne, Dollet, Michel, Fabre, Sandrine, Jaillon, Olivier, Noël, Benjamin, Poulain, Julie, Wincker, Patrick   +9 more
core  

Genome-Wide Association Study for Chronic Hepatitis B Infection in the Thai Population

Frontiers in Genetics, 2022
To identify novel host genetic variants that predispose to hepatitis B virus (HBV) persistence, we performed the first genome-wide association study in the Thai population involving 318 cases of chronic hepatitis B and 309 healthy controls after quality ...
Saeideh Ashouri, Saeideh Ashouri, Seik-Soon Khor, Seik-Soon Khor, Yuki Hitomi, Hiromi Sawai, Nao Nishida, Masaya Sugiyama, Yosuke Kawai, Yosuke Kawai, Nawarat Posuwan, Nawarat Posuwan, Pisit Tangkijvanich, Piyawat Komolmit, Piyawat Komolmit, Makoto Tsuiji, Vorasuk Shotelersuk, Yong Poovorawan, Masashi Mizokami, Katsushi Tokunaga, Katsushi Tokunaga   +20 more
doaj   +1 more source

Supplementary Table from Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma [PDF]

, 2023
Parvathi Sudha, Aarif Ahsan, Cody Ashby, Tasneem Kausar, Akhil Khera, Mohammad H. Kazeroun, Chih-Chao Hsu, Lin Wang, Evelyn Fitzsimons, Outi Salminen, Patrick Blaney, Magdalena Czader, Jonathan Williams, Mohammad Abu Zaid, Naser Ansari‐Pour, Kwee Yong, Frits van Rhee, William E. Pierceall, Gareth J. Morgan, Erin Flynt, Sarah Gooding, Rafat Abonour, Karthik Ramasamy, Anjan Thakurta, Brian A. Walker   +24 more
openalex   +1 more source

The role of the interactome in the maintenance of deleterious variability in human populations

Molecular Systems Biology, 2014
Recent genomic projects have revealed the existence of an unexpectedly large amount of deleterious variability in the human genome. Several hypotheses have been proposed to explain such an apparently high mutational load. However, the mechanisms by which
Luz Garcia‐Alonso, Jorge Jiménez‐Almazán, Jose Carbonell‐Caballero, Alicia Vela‐Boza, Javier Santoyo‐López, Guillermo Antiñolo, Joaquin Dopazo   +6 more
doaj   +1 more source

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

eLife, 2014
Recent sequencing studies have extensively explored the somatic alterations present in the nuclear genomes of cancers. Although mitochondria control energy metabolism and apoptosis, the origins and impact of cancer-associated mutations in mtDNA are ...
Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien, Niccolo Bolli, Sam Behjati, Patrick S Tarpey, Jyoti Nangalia, Charles E Massie, Adam P Butler, Jon W Teague, George S Vassiliou, Anthony R Green, Ming-Qing Du, Ashwin Unnikrishnan, John E Pimanda, Bin Tean Teh, Nikhil Munshi, Mel Greaves, Paresh Vyas, Adel K El-Naggar, Tom Santarius, V Peter Collins, Richard Grundy, Jack A Taylor, D Neil Hayes, David Malkin, ICGC Breast Cancer Group, ICGC Chronic Myeloid Disorders Group, ICGC Prostate Cancer Group, Christopher S Foster, Anne Y Warren, Hayley C Whitaker, Daniel Brewer, Rosalind Eeles, Colin Cooper, David Neal, Tapio Visakorpi, William B Isaacs, G Steven Bova, Adrienne M Flanagan, P Andrew Futreal, Andy G Lynch, Patrick F Chinnery, Ultan McDermott, Michael R Stratton, Peter J Campbell   +52 more
doaj   +1 more source

Biological Machine Learning Combined with Campylobacter Population Genomics Reveals Virulence Gene Allelic Variants Cause Disease

Microorganisms, 2020
Highly dimensional data generated from bacterial whole-genome sequencing is providing an unprecedented scale of information that requires an appropriate statistical analysis framework to infer biological function from populations of genomes.
DJ Darwin R. Bandoy, Bart C. Weimer
doaj   +1 more source

Narcolepsy type I-associated DNA methylation and gene expression changes in the human leukocyte antigen region

Scientific Reports, 2023
Narcolepsy type 1 (NT1) is caused by a loss of hypothalamic orexin-producing cells, and autoreactive CD4+ and CD8+ T cells have been suggested to play a role in the autoimmune mechanism.
Kugui Yoshida-Tanaka, Mihoko Shimada, Yoshiko Honda, Akihiro Fujimoto, Katsushi Tokunaga, Makoto Honda, Taku Miyagawa   +6 more
doaj   +1 more source

Artificial and Natural Genetic Information Processing [PDF]

, 2017
Conventional methods of genetic engineering and more recent genome editing techniques focus on identifying genetic target sequences for manipulation.
Witzany, Guenther
core  

Knowledge, attitudes and decision regret: a longitudinal survey study of participants offered genome sequencing in the 100,000 Genomes Project [PDF]

, 2023
Michelle Peter, Jennifer Hammond, Saskia C. Sanderson, Jana Gurasashvili, Amy Hunter, Beverly Searle, Christine Patch, Lyn S. Chitty, Melissa Hill, Celine Lewis   +9 more
openalex   +1 more source

Nutritional Stress Leads to Persistence and Persister-like Growth in Staphylococcus aureus

Pathogens
Staphylococcus aureus is a versatile zoonotic pathogen capable of causing a wide range of infections. Due to the organism’s ability to persist, recalcitrant and recurring infections are a major concern for public and animal health.
Katie R. Risoen, Claire A. Shaw, Bart C. Weimer   +2 more
doaj   +1 more source