Results 81 to 90 of about 11,389,397 (311)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Justice and the human genome project

, 1994
The Human Genome Project is an expensive, ambitious, and controversial attempt to locate and map every one of the approximately 100,000 genes in the human body.
Murphy, Timothy F 1955-, Lappé, Marc, Human Genome Project., Human Genome Project   +3 more
core  

Draft Genome Sequence of Marinobacter sp. Strain P4B1, an Electrogenic Perchlorate-Reducing Strain Isolated from a Long-Term Mixed Enrichment Culture of Marine Bacteria

, 2016
The perchlorate-reducing strain Marinobacter sp. strain P4B1 was isolated from a long-term perchlorate-degrading enrichment culture seeded with marine sediment. The draft genome of Marinobacter sp. P4B1 is comprised of the bacterial chromosome (3.60 Mbp,
Roberts, Deborah J., Xiao, Yeyuan, Fox, George E., Stepanov, Victor G., Lopez, April J.   +4 more
core   +1 more source

An improved genome of the model marine alga Ostreococcus tauri unfolds by assessing Illumina de novo assemblies [PDF]

, 2014
Background: Cost effective next generation sequencing technologies now enable the production of genomic datasets for many novel planktonic eukaryotes, representing an understudied reservoir of genetic diversity. O.
Moreau, Hervé, Van De Peer, Yves, Adam Eyre-Walker, Château, Annie, Van de Peer, Y., Stephane Rombauts, Carré, Isabelle, Eyre-Walker, Adam, Rivals, E., Peer, Yves van de, Wendy Schackwitz, Schackwitz, Wendy, Benoit Piégu, Moreau, H., Schackwitz, W., Grimsley, Nigel, Evelyne Derelle, Rombauts, Stephane, Eyre Walker, Adam, Blanc-Mathieu, R., Eyre-Walker, A., Verhelst, B., Blanc-Mathieu, Romain, Bouget, François-Yves, Hervé Moreau, Nigel Grimsley, Rivals, Eric, Piégu, Benoit, Isabelle Carré, François-Yves Bouget, Derelle, Evelyne, Eric Rivals, Carré, I., Gwenaël Piganeau, Derelle, E., Bram Verhelst, Verhelst, Bram, Annie Château, Romain Blanc-Mathieu, Bouget, F.-Y., Château, A., Carré, Isabelle A., Piégu, B., Grimsley, N., Piganeau, G., Rombauts, S., Piganeau, Gwenaël, Blanc Mathieu, Romain, Yves Van de Peer   +48 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Legal Problems: Human Genome Project

, 1993
Conference on Legal Aspects of the Human Genome Project in Bilbao, Spain; May 24-26 ...
Kirby, Michael
core  

Draft genome sequence of Komagataeibacter rhaeticus Strain AF1, a high producer of cellulose, isolated from kombucha tea

, 2014
Here, we present the draft genome sequence of Komagatabaeicter rhaeticus strain AF1, which was isolated from Kombucha tea and is capable of producing high levels of cellulose.Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Laboratório ...
Santos, Renato Augusto Corrêa dos, Zucchi, Tiago Domingues, dos Santos, Renato Augusto Corrêa, Berretta, Andresa A., Ribeiro, Sidney José Lima [UNESP], Goldman, Gustavo H., Barud, Hernane da Silva [UNESP], González-García, Laura Natalia, Riaño-Pachón, Diego M., Ribeiro, Sidney José Lima, Barud, Hernane da Silva   +10 more
core   +1 more source

The Amborella genome and the evolution of flowering plants [PDF]

, 2013
Amborella trichopoda is strongly supported as the single living species of the sister lineage to all other extant flowering plants, providing a unique reference for inferring the genome content and structure of the most recent common ancestor (MRCA) of ...
Genome Project, Amborella, Carretero Paulet, Lorenzo   +1 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Case Report: Shift from Aggressive Periodontitis to Feline Chronic Gingivostomatitis Is Linked to Increased Microbial Diversity

Pathogens
Aggressive Periodontitis (AP) and Feline Chronic Gingivostomatitis (FCGS) are two oral inflammatory diseases in cats with unknown etiology. Both conditions present with severe inflammation of the oral cavity and in FCGS it is found with additional ...
Claire A. Shaw, Maria Soltero-Rivera, Rodrigo Profeta, Bart C. Weimer   +3 more
doaj   +1 more source