Results 81 to 90 of about 743,811 (309)

The map-based sequence of the rice genome

, 2005
Rice, one of the world's most important food plants, has important syntenic relationships with the other cereal species and is a model plant for the grasses.
International Rice Genome Sequencing Project,
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Legal Problems: Human Genome Project

, 1993
Conference on Legal Aspects of the Human Genome Project in Bilbao, Spain; May 24-26 ...
Kirby, Michael
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The human genome project: perilous promises?

, 1999
review of PLAIN TALK ABOUT THE HUMAN GENOME PROJECT, by E. Smith and W.
Lippman, Abby
core  

Harvard Personal Genome Project: lessons from participatory public research [PDF]

, 2014
Background: Since its initiation in 2005, the Harvard Personal Genome Project has enrolled thousands of volunteers interested in publicly sharing their genome, health and trait data.
Ward Vandewege, Chou, Michael, Michael F Chou, Alexander Zaranek, George M Church, Jason R Bobe, Zaranek, Alexander Wait, Estep, Preston W, Clegg, Tom, Bobe, Jason R, Church, George, Madeleine P Ball, Tom Clegg, Jeantine E Lunshof, Ball, Madeleine, Vandewege, Ward, Preston W Estep, Lunshof, Jeantine   +17 more
core   +1 more source

Case Report: Shift from Aggressive Periodontitis to Feline Chronic Gingivostomatitis Is Linked to Increased Microbial Diversity

Pathogens
Aggressive Periodontitis (AP) and Feline Chronic Gingivostomatitis (FCGS) are two oral inflammatory diseases in cats with unknown etiology. Both conditions present with severe inflammation of the oral cavity and in FCGS it is found with additional ...
Claire A. Shaw, Maria Soltero-Rivera, Rodrigo Profeta, Bart C. Weimer   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Genomics and the Human Genome Project

, 2012
This OER consists of an instructional sheet produced by GENIE CETL in the Department of Genetics. By the end of this material you should have learnt about: The genome of an organism i.e.
GENIE CETL
core  

Case Report: Inflammation-Driven Species-Level Shifts in the Oral Microbiome of Refractory Feline Chronic Gingivostomatitis

Bacteria
The cat oral microbiome plays an important role in maintaining host health, yet little is known about how to apply microbial data in a clinical setting.
Claire A. Shaw, Maria Soltero-Rivera, Rodrigo Profeta, Bart C. Weimer   +3 more
doaj   +1 more source