Results 11 to 20 of about 1,117,067 (265)

Cross-Border Transmissions of the Delta Substrain AY.29 During Tokyo Olympic and Paralympic Games

open access: yesFrontiers in Microbiology, 2022
Tokyo Olympic and Paralympic Games, postponed for the COVID-19 pandemic, were finally held in the summer of 2021. Just before the games, the Alpha variant was being replaced with the more contagious Delta variant.
Takahiko Koyama   +6 more
doaj   +1 more source

The Newfoundland and Labrador mosaic founder population descends from an Irish and British diaspora from 300 years ago

open access: yesCommunications Biology, 2023
The founder population of Newfoundland and Labrador (NL) is a unique genetic resource, in part due to its geographic and cultural isolation, where historical records describe a migration of European settlers, primarily from Ireland and England, to NL in ...
Edmund Gilbert   +17 more
doaj   +1 more source

Genomic sequencing. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1984
Unique DNA sequences can be determined directly from mouse genomic DNA. A denaturing gel separates by size mixtures of unlabeled DNA fragments from complete restriction and partial chemical cleavages of the entire genome. These lanes of DNA are transferred and UV-crosslinked to nylon membranes.
Church, George, Gilbert, Walter
openaire   +4 more sources

Analyzing integrated network of methylation and gene expression profiles in lung squamous cell carcinoma

open access: yesScientific Reports, 2022
Gene expression, DNA methylation, and their organizational relationships are commonly altered in lung squamous cell carcinoma (LUSC). To elucidate these complex interactions, we reconstructed a differentially expressed gene network and a differentially ...
Yusri Dwi Heryanto   +2 more
doaj   +1 more source

Linearization of genome sequence graphs revisited

open access: yesiScience, 2021
Summary: The need to include the genetic variation within a population into a reference genome led to the concept of a genome sequence graph. Nodes of such a graph are labeled with DNA sequences occurring in represented genomes.
Anna Lisiecka, Norbert Dojer
doaj   +1 more source

The Genome Sequence DataBase [PDF]

open access: yesNucleic Acids Research, 2000
The Genome Sequence DataBase (GSDB) is a database of publicly available nucleotide sequences and their associated biological and bibliographic information. Several notable changes have occurred in the past year: GSDB stopped accepting data submissions from researchers; ownership of data submitted to GSDB was transferred to GenBank; sequence analysis ...
Carol Harger   +8 more
openaire   +2 more sources

Sequencing the human genome [PDF]

open access: yesNature, 1986
The title of the report by R. Myerowitz and N. Hogikyan on page 1646 of the issue of 27 June was incorrect. It should have been "Different mutations in Ashkenazi Jews and non-Jewish French Canadians with Tay-Sachs disease."
J B, Walsh, J, Marks
openaire   +4 more sources

Sequencing technologies and genome sequencing [PDF]

open access: yesJournal of Applied Genetics, 2011
The high-throughput - next generation sequencing (HT-NGS) technologies are currently the hottest topic in the field of human and animals genomics researches, which can produce over 100 times more data compared to the most sophisticated capillary sequencers based on the Sanger method.
Pareek, Chandra Shekhar   +2 more
openaire   +3 more sources

Whole-genome sequencing [PDF]

open access: yesPractical Neurology, 2021
The costs of whole-genome sequencing have rapidly decreased, and it is being increasingly deployed in large-scale clinical research projects and introduced into routine clinical care. This will lead to rapid diagnoses for patients with genetic disease but also introduces uncertainty because of the diversity of human genomes and the potential ...
Huw R Morris, Henry Houlden, James Polke
openaire   +3 more sources

GSAlign: an efficient sequence alignment tool for intra-species genomes

open access: yesBMC Genomics, 2020
Background Personal genomics and comparative genomics are becoming more important in clinical practice and genome research. Both fields require sequence alignment to discover sequence conservation and variation.
Hsin-Nan Lin, Wen-Lian Hsu
doaj   +1 more source

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