Results 161 to 170 of about 8,007,177 (368)

Direction of Translation and Size of Bacteriophage [var phi]X174 Cistrons [PDF]

open access: yes, 1972
Translation of the bacteriophage [var phi]X174 genome follows cistron order D-E-F-G-H-A-B-C. To establish this, the position of a nonsense mutation on the genetic map was compared with the physical size (molecular weight) of the appropriate protein ...
Benbow, Robert M.   +3 more
core  

Inferring human population size and separation history from multiple genome sequences

open access: yesNature Genetics, 2014
The availability of complete human genome sequences from populations across the world has given rise to new population genetic inference methods that explicitly model ancestral relationships under recombination and mutation.
S. Schiffels, R. Durbin
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Genome-Based Taxonomic Classification of the Phylum Actinobacteria

open access: yesFrontiers in Microbiology, 2018
The application of phylogenetic taxonomic procedures led to improvements in the classification of bacteria assigned to the phylum Actinobacteria but even so there remains a need to further clarify relationships within a taxon that encompasses organisms ...
Imen Nouioui   +9 more
doaj   +1 more source

Comparative genomics of brain size evolution [PDF]

open access: yesFrontiers in Human Neuroscience, 2014
Which genetic changes took place during mammalian, primate and human evolution to build a larger brain? To answer this question, one has to correlate genetic changes with brain size changes across a phylogeny. Such a comparative genomics approach provides unique information to better understand brain evolution and brain development.
openaire   +5 more sources

Factors driving effective population size and pan-genome evolution in bacteria

open access: yesBMC Evolutionary Biology, 2018
Knowledge of population-level processes is essential to understanding the efficacy of selection operating within a species. However, attempts at estimating effective population sizes (Ne) are particularly challenging in bacteria due to their extremely ...
L. Bobay, H. Ochman
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Estimate of the Genome Size by Renaturation Studies in Streptomyces [PDF]

open access: gold, 1975
Romualdo Benigni   +2 more
openalex   +1 more source

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