Verification of the chromosome number using cytogenetics and estimation of genome size via flow cytometry and k-mer analyses for representative Anoectochilus roxburghii accessions. [PDF]
Zhang W, Mei Y, Wang J.
europepmc +1 more source
Integration of Bioengineered Tools in Assisted Reproductive Technologies
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak+3 more
wiley +1 more source
Compression rates of microbial genomes are associated with genome size and base composition. [PDF]
Bohlin J, Pettersson JH.
europepmc +1 more source
Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja+6 more
wiley +1 more source
findGSEP: estimating genome size of polyploid species using k-mer frequencies. [PDF]
Fu L+7 more
europepmc +1 more source
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua+9 more
wiley +1 more source
Cytogenetic diversity of the diploid Korean wild Chrysanthemum (Asteraceae) inferred from genome size variations and chromosomal distributions of 5 S and 18 S rDNAs. [PDF]
Kang JH, Moon MJ, Kim JS.
europepmc +1 more source
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan+13 more
wiley +1 more source
Comparative Analysis of the Chloroplast Genomes of Cypripedium: Assessing the Roles of SSRs and TRs in the Non-Coding Regions of LSC in Shaping Chloroplast Genome Size. [PDF]
Liu H+8 more
europepmc +1 more source