Results 41 to 50 of about 1,002,761 (261)

A dormant resource for genome size estimation in ferns: C‐value inference of the Ophioglossaceae using herbarium specimen spores

Applications in Plant Sciences, 2021
Premise The great variation of genome size (C‐value) across land plants is linked to various adaptative features. Flow cytometry (FCM), the standard approach to estimating C‐values, relies mostly on fresh materials, performing poorly when used with ...
Li‐Yaung Kuo, Sheng Kai Tang, Tzu‐Tong Kao, Atsushi Ebihara, Susan Fawcett, Min‐Chien Hsiao, Wataru Shinohara, Benjamin Dauphin   +7 more
doaj   +1 more source

Genome Streamlining: Effect of Mutation Rate and Population Size on Genome Size Reduction. [PDF]

Genome Biol Evol
Abstract Genome streamlining, i.e. genome size reduction, is observed in bacteria with very different life traits, including endosymbiotic bacteria and several marine bacteria, raising the question of its evolutionary origin. None of the hypotheses proposed in the literature is firmly established, mainly due to the many confounding ...
Luiselli J, Rouzaud-Cornabas J, Lartillot N, Beslon G.   +3 more
europepmc   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The evolution of genome size in ants [PDF]

BMC Evolutionary Biology, 2008
Despite the economic and ecological importance of ants, genomic tools for this family (Formicidae) remain woefully scarce. Knowledge of genome size, for example, is a useful and necessary prerequisite for the development of many genomic resources, yet it has been reported for only one ant species (Solenopsis invicta), and the two published estimates ...
Tsutsui, Neil D, Suarez, Andrew V, Spagna, Joseph C, Johnston, J Spencer   +3 more
openaire   +4 more sources

Rooibos (Aspalathus linearis) Genome Size Estimation Using Flow Cytometry and K-Mer Analyses

Plants, 2020
Plant genomes provide information on biosynthetic pathways involved in the production of industrially relevant compounds. Genome size estimates are essential for the initiation of genome projects.
Yamkela Mgwatyu, Allison Anne Stander, Stephan Ferreira, Wesley Williams, Uljana Hesse   +4 more
doaj   +1 more source

Intragenomic Conflict between Knob Heterochromatin and B Chromosomes Is the Key to Understand Genome Size Variation along Altitudinal Clines in Maize

Plants, 2021
In maize, we studied the causes of genome size variation and their correlates with cultivation altitude that suggests the existence of adaptive clines.
Graciela Esther González, Lidia Poggio
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genome size variation in Tardigrada [PDF]

Zoological Journal of the Linnean Society, 1996
Abstract The genome size of tardigrades has been documented to date in seven species of eutardigrades, and it is among the lowest in invertebrates. In this paper the evaluation of genome size is extended to eight other species of eutardigrades and to one species of heterotardigrades, in order to obtain a more comprehensive picture of minimum DNA ...
S. GARAGNA, REBECCHI, Lorena, A. GUIDI
openaire   +2 more sources