Results 1 to 10 of about 400,024 (219)
Functional Genomic Characterization of Cancer Genomes [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2016 International efforts to sequence cancer genomes now provide an overview of the major genetic alterations that occur in most human cancers. These studies have identified many highly recurrent alterations in specific cancer subtypes but have also identified mutations that occur at lower frequency and unstudied variants of known cancer-associated genes ...
Thomas P, Howard +7 more
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Genomic Characterization of Acute Leukemias [PDF]
Medical Principles and Practice, 2014 Over the past two decades, hematologic malignancies have been extensively evaluated due to the introduction of powerful technologies, such as conventional karyotyping, FISH analysis, gene and microRNA expression profiling, array comparative genomic hybridization and SNP arrays, and next-generation sequencing (including whole-exome sequencing and RNA ...
CHIARETTI, sabina +3 more
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Genomic and functional characterization of StCDPK1 [PDF]
Plant Molecular Biology, 2009 StCDPK1 is a calcium dependent protein kinase expressed in tuberizing potato stolons and in sprouting tubers. StCDPK1 genomic sequence contains eight exons and seven introns, the gene structure is similar to Arabidopsis, rice and wheat CDPKs belonging to subgroup IIa.
Gargantini, Pablo Ruben +5 more
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Genomic characterization of the Yersinia genus [PDF]
Genome Biology, 2010 Abstract Background New DNA sequencing technologies have enabled detailed comparative genomic analyses of entire genera of bacterial pathogens. Prior to this study, three species of the enterobacterial genus Yersinia that cause invasive human diseases (Yersinia pestis, Yersinia pseudotuberculosis, and ...
Chen, P.E +15 more
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Genomic characterization of perturbation sensitivity [PDF]
Bioinformatics, 2007 Abstract Motivation: In determining the function of a gene, it provides much information to observe the changes in a biological system after disruption of the gene of interest through its knockout. Thanks to the microarray technology, it is now possible to profile transcriptional changes of the whole genome, thus differentiating genes ...
Jung Hun Ohn, Jihun Kim 0001, Ju Han Kim
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Characterization of the genome of Arabidopsis thaliana [PDF]
Journal of Molecular Biology, 1986 The small crucifer Arabidopsis thaliana has many useful features as an experimental organism for the study of plant molecular biology. It has a four-week life-cycle, only five chromosomes and a genome size less than half that of Drosophila. To characterize the DNA sequence organization of this plant, we have randomly selected 50 recombinant lambda ...
Pruitt, Robert E., Meyerowitz, Elliot M.
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MOLECULAR CHARACTERIZATION OF THE DROSOPHILA GENOME [PDF]
Genetics, 1969 A remarkable feature of evolution in the genus Drosophila is the conservation of the basic karyotype. Postulation of Robertsonian centric fusions (ROBERTSON 1916) is sufficient to explain most of the karyotypic rearrangements found in the various species.
C D, Laird, B J, McCarthy
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Characterization of the genome of bald cypress [PDF]
BMC Genomics, 2011 AbstractBackgroundBald cypress (Taxodium distichum var. distichum) is a coniferous tree of tremendous ecological and economic importance. It is a member of the family Cupressaceae which also includes cypresses, redwoods, sequoias, thujas, and junipers.
Liu Wenxuan +4 more
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Genomic Characterization of the Istrian Shorthaired Hound [PDF]
Animals, 2020 Istrian shorthaired hound is an old indigenous Croatian dog breed with historical traces of its origin, which date back to the 14th century. Due to its intelligence and great hunting abilities, it is considered an excellent hunting dog. Despite its ancient origin, there is no data on genetic diversity, population structure, and degree of inbreeding ...
Ivona Djurkin Kušec +6 more
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Genomic Characterization of the Taylorella Genus
PLoS ONE, 2012 The Taylorella genus comprises two species: Taylorella equigenitalis, which causes contagious equine metritis, and Taylorella asinigenitalis, a closely-related species mainly found in donkeys. We herein report on the first genome sequence of T. asinigenitalis, analyzing and comparing it with the recently-sequenced T. equigenitalis genome.
Hébert, Laurent +9 more
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