Results 151 to 160 of about 441,826 (314)

Comparative Genomic Hybridization of Human Malignant Gliomas Reveals Multiple Amplification Sites and Nonrandom Chromosomal Gains and Losses [PDF]

, 1994
Nine human malignant gliomas (2 astrocytomas grade III and 7 glioblastomas) were analyzed using comparative genomic hybridization (CGH). In addition to the amplification of the EGFR gene at 7p12 in 4 of 9 cases, six new amplification sites were mapped to
Vogel, S., Ried, Thomas, Thiel, G., Manoir, Stanislas du, Meffert, M. C., Speicher, Michael R., Cremer, Thomas, Donis-Keller, Helen, Nürnberg, P., Lozonova, T., Jauch, Anna, Schröck, Evelin, Witkowski, R., Jänisch, W.   +13 more
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Corrigendum: Antimicrobial resistance and genomic characterization of Escherichia coli from pigs and chickens in Zhejiang, China

Frontiers in Microbiology, 2023
Wei Zhou, Rumeng Lin, Rumeng Lin, Rumeng Lin, Zhijin Zhou, Jiangang Ma, Hui Lin, Hui Lin, Xue Zheng, Jingge Wang, Jing Wu, Yuzhi Dong, Yuzhi Dong, Han Jiang, Hua Yang, Zhangnv Yang, Biao Tang, Min Yue   +17 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species

, 2010
Background: The genus Cronobacter (formerly called Enterobacter sakazakii) is composed of five species; C. sakazakii, C. malonaticus, C. turicensis, C. muytjensii, and C. dublinensis.
Wilson, Richard K, Feng, Dongyan, Forsythe, Stephen J, Nash William E., Xia, Xiao-Qin, Forsythe, SJ, Long Fred, Catrina Fronick, Kyung Kim, Kim Kyung, Warren, Wesley, Lucinda Fulton, Warren Wesley, Fronick, Catrina, Sandra W Clifton, Shah Neha, Kucerova, Eva, Shah, Neha, Eva Kucerova, Kyung, K, Fronick Catrina, Wilson Richard K., Fulton Robert, Feng Dongyan, Forsythe Stephen J., Minx, P, Hallsworth-Pepin, Kymberlie, Xiao-Qin Xia, Porwollik Steffen, Long, F, Steffen Porwollik, Wilson, RK, Michael McClelland, Dongyan Feng, Fulton, L, Neha Shah, Fronick, C, Wollam Aye, Kucerova, E, McClelland Michael, Fulton, R, Nash, WE, Nash, William E, Patrick Minx, Clifton Sandra W., Fred Long, Long, Fred, Bhonagiri Veena, Hallsworth-Pepin Kymberlie, Wollam, Aye, Warren, W, Wesley Warren, Hallsworth-Pepin, K, Fulton, Lucinda, Xia Xiao-Qin, Bhonagiri, Veena, Kymberlie Hallsworth-Pepin, Fulton Lucinda, Minx, Patrick, Shah, N, Minx Patrick, Veena Bhonagiri, Fulton, Robert, Xia, XQ, Bhonagiri, V, William E Nash, Kyung, Kim, Porwollik, S, McClelland, Michael, Wollam, A, Robert Fulton, Feng, D, Clifton, Sandra W, Aye Wollam, Kucerova Eva, Stephen J Forsythe, Clifton, SW, Richard K Wilson, McClelland, M, Porwollik, Steffen   +79 more
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Identification, antifungal resistance, and genomic characterization of a single Candida auris isolate from urinary tract infection

Frontiers in Cellular and Infection Microbiology
ObjectiveTo analyze the identification, antifungal resistance, and genomic characteristics of a Candida auris (C. auris) strain isolated from a urine specimen of an ICU patient at Yijishan Hospital, Wannan Medical College, Anhui Province.MethodsThe ...
Jie Li, Ziheng Wang, Rui Zheng, Yangyan Wang, Xin Guo, Xiaoning Li, Peng Zhang   +6 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Molecular characterization and detection of infectious bronchitis virus [PDF]

, 2012
This thesis deals with the molecular characterization and detection of infectious bronchitis virus (IBV), an important pathogen that causes heavy losses in the poultry populations worldwide.
Abro, Shahid Hussain
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Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication-5

, 2011
Copyright information:Taken from "Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication"BMC Genomics 2006;7():74-74.Published online 5 Apr 2006PMCID:PMC1458327.Copyright © 2006 Qian et al ...
Yanbin Yin (5908), Ziliang Qian (36887), Yong Zhang (5893), Yixue Li (18673), Lingyi Lu (64575), Ying Jiang (5910)   +5 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Genomic characterization of metastatic breast cancers.

, 2019
Metastasis is the main cause of death for patients with breast cancer. Many studies have characterized the genomic landscape of breast cancer during its early stages.
Bachelot, Thomas, Guillaume Meurice, Le Tourneau, Christophe, Jimenez, Marta, Fabrice André, Claudia Lefeuvre, Chaffanet, Max, Mario Campone, Adnani, Yahia, Herve Bonnefoi, Alicia Tran Dien, Nadine Carbuccia, Filleron, Thomas, Ng, Kiu Yan Charlotte, Thomas Bachelot, Jean Charles Soria, Yahia Adnani, Droin, Nathalie, Anne Patsouris, Campone, Mario, Birnbaum, Daniel, Charlotte K. Y. Ng, Kamal, Maud, Dogan, Semih, Christophe Le Tourneau, Lefeuvre, Claudia, Maud Kamal, Marta Jimenez, De Filippo, Maria R, Daniel Birnbaum, Nathalie Droin, Carbuccia, Nadine, Thomas Filleron, Maria R. De Filippo, Verret, Benjamin, Garnier, Séverine, Dien, Alicia Tran, Benjamin Verret, François Bertucci, Soria, Jean Charles, Salvatore Piscuoglio, Alexandra Jacquet, Meurice, Guillaume, Patsouris, Anne, Naveen Babbar, Jacquet, Alexandra, Ng, Charlotte, Max Chaffanet, André, Fabrice, Semih Dogan, de Filippo, Maria, Séverine Garnier, Bertucci, François, Dalenc, Florence, Florence Dalenc, Piscuoglio, Salvatore, Bonnefoi, Herve, Babbar, Naveen   +57 more
core   +1 more source