Results 131 to 140 of about 2,956,729 (308)

The effect of genomic information on optimal contribution selection in livestock breeding programs [PDF]

, 2013
Long-term benefits in animal breeding programs require that increases in genetic merit be balanced with the need to maintain diversity (lost due to inbreeding). This can be achieved by using optimal contribution selection.
Hickey, John M, Clark, Samuel A, John M Hickey, Brian P Kinghorn, van der Werf, Julius Hj, Samuel A Clark, Julius HJ van der Werf, Kinghorn, Brian P   +7 more
core   +1 more source

Rapid Genomic Characterization of the Genus Vitis

PLoS ONE, 2010
Next-generation sequencing technologies promise to dramatically accelerate the use of genetic information for crop improvement by facilitating the genetic mapping of agriculturally important phenotypes. The first step in optimizing the design of genetic mapping studies involves large-scale polymorphism discovery and a subsequent genome-wide assessment ...
Sean Myles, Jer-Ming Chia, Bonnie Hurwitz, Charles Simon, Gan Yuan Zhong, Edward Buckler, Doreen Ware   +6 more
openaire   +4 more sources

Genomic footprint of a shared Type 5 prophage in “Candidatus Liberibacter asiaticus” and “Candidatus Liberibacter africanus,” two destructive bacterial pathogens of citrus Huanglongbing

Applied and Environmental Microbiology
Huanglongbing (HLB) is a bacterial disease that affects citrus trees and is considered the most severe citrus disease in the world. The three HLB-associated “Ca.
Frédéric Labbé, Claudine Boyer, Fernando Clavijo-Coppens, Blandine Benoist, Patrick Turpin, Santatra Ravelomanantsoa, Olivier Pruvost   +6 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Studies on polymorphic alu insertions and genomic diversity within the major histocompatibility complex [PDF]

, 2005
After the initiation of the human genome sequencing project and the introduction of the field of 'bioinformatics', interest in human genetic diversity studies has been increased.
Dunn, David Suliman
core  

Genomic Characterization of Papillary Thyroid Carcinoma: Age Differences in Tumor Aggressiveness and Immune Infiltration

Diagnostics
Background: Adolescents and young adults (AYA) with papillary thyroid carcinoma (PTC) often present with more extensive cervical lymph node metastasis (LNM) than older adults (AD).
Wei Ao, Shuqian Chen, Tenghong Liu, Bo Wang, Wenxin Zhao   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Trans-ethnic comprehensive genomic cluster stratification of upper tract urothelial carcinoma

[[abstract]]Introduction & Objectives: Previous genomic studies on upper tract urothelial carcinoma (UTUC) revealed characteristics compared to urinary bladder urothelial carcinoma (UBUC), but no endemic and epidemiologic specialties.
Wei, TC;Lin, YF;Luo, HL;Chang, YH;Ohyama, C;Hatakeyama, S;Huang, WJ;Wang, HJ;Yoneyama, T;Tsai, SF
core   +1 more source

Fast and sensitive multiple alignment of large genomic sequences [PDF]

, 2003
Brudno M, Chapman M, Göttgens B, Batzoglou S, Morgenstern B. Fast and sensitive multiple alignment of large genomic sequences. BMC Bioinformatics.
Brudno, Michael, Batzoglou, S., Chapman, Mark A., Göttgens, Berthold, Batzoglou, Serafim, Morgenstern, Burkhard, Gottgens, B., Chapman, Michael, Berthold Göttgens, Brudno, M., Burkhard Morgenstern, Michael Chapman, Michael Brudno, Serafim Batzoglou   +13 more
core   +3 more sources

Isolation and Genomic Characterization of Two Lytic Cutibacterium acnes Phages Defines Two Novel Pahexavirus Species

Viruses
Bacteriophages are promising antibacterial agents for managing acne vulgaris caused by Cutibacterium acnes, particularly given increasing antibiotic resistance.
Anastasia A. Vorobeva, Aleksei M. Vorobev, Peter V. Evseev, Emil R. Mekhtiev, Andrei V. Chaplin, Maria A. Pasivkina, Ekaterina S. Zubkova, Svetlana S. Bochkareva, Mikhail A. Yaitsky, Nikolai A. Nikitin, Natalia B. Demina, Victoria A. Korol, Andrei V. Aleshkin, Anatolij N. Blintsov, Maria N. Anurova   +14 more
doaj   +1 more source