Results 181 to 190 of about 441,826 (314)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Complete genome sequence of the Medicago microsymbiont Ensifer (Sinorhizobium) medicae strain WSM419

, 2010
Ensifer (Sinorhizobium) medicae is an effective nitrogen fixing microsymbiont of a diverse range of annual Medicago (medic) species. Strain WSM419 is an aerobic, motile, non-spore forming, Gram-negative rod isolated from a M.
Land, M., Markowitz, V., Copeland, A., Gollagher, M., Dilworth, M.J., Reeve, W.G., O'Hara, G.W., Nandasena, K.G., Nolan, M., Chang, Y-J, Mavromatis, K., Ardley, J.K., Malfatti, S., Kyrpides, N, Ivanova, N., Tiwari, R., Lapidus, A., Kiss, H., Howieson, J.G., Yates, R.J., Hauser, L., Chain, P., Bräu, L.   +22 more
core  

Detection and Genomic Characterization of Senecavirus A, Ohio, USA, 2015

Emerging Infectious Diseases, 2016
Leyi Wang, Melanie Prarat, Jeff Hayes, Yan Zhang   +3 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Genomic Characterization of IS Insertions in

Evolutionary Bioinformatics
Mycobacterium orygis , a subspecies of the Mycobacterium tuberculosis complex (MTBC), has emerged as a significant concern in the context of One Health, with implications for zoonosis or zooanthroponosis or both. MTBC strains are characterized by the unique insertion element IS 6110 , which is widely used as a diagnostic marker.
Ahmed Kabir Refaya, Umashankar Vetrivel, Kannan Palaniyandi   +2 more
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Genomic Characterization of Yersinia enterocolitica Isolates, Costa Rica

International audienceData on enteric yersinioses in Central America are limited. Genomic characterization of 78 Yersinia enterocolitica isolates from Costa Rica indicated persistent infection-source circulation between animal reservoirs and humans, as ...
Pizarro-Cerdá, Javier, Rivas-Solano, Olga, Oropeza, Gletty, Chanto, Grettel, Savin, Cyril, Barboza Fallas, Luis   +5 more
core   +1 more source

Molecular surveillance and genomic characterization of enterovirus D68 in southern Portugal, 2024-2025. [PDF]

Arch Virol
Santos-Silva S, Moreira G, Palma A, Rodrigues S, Simões M, Guerreiro R, Nascimento MSJ, Mesquita JR.   +7 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

A comprehensive genomic characterization of Nellore cattle. [PDF]

BMC Genomics
Campos G, Mulim H, Ventura H, Souza N, Cardoso F, de Oliveira HR.   +5 more
europepmc   +1 more source