Results 201 to 210 of about 821,530 (308)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Pathogenicity and genomic characterization of Brazilian fowl adenovirus serotypes 1 and 11. [PDF]

Poult Sci
Zani GS, Esteves PA, Caron L, Trevisol IM, Barbosa AO, Mores MAZ, Junqueira DM, Demoliner M, Spilki FR, Fischer G, de Lima M.   +10 more
europepmc   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Genomic Characterization of Lung Cancer in Never-Smokers Using Deep Learning. [PDF]

Mod Pathol
Saha M, Tran TV, Bhawsar PM, Zhang T, Zhao W, Hoang PH, Mutreja K, Lawrence SM, Rothman N, Lan Q, Homer R, Baine MK, Sholl LM, Joubert P, Leduc C, Travis WD, Chanock SJ, Shi J, Yang SR, Almeida JS, Landi MT.   +20 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Genomic characterization, annotation, and comparative analysis of Ludisia discolor reveal its evolutionary and functional traits. [PDF]

Planta
Yang Q, Cai K, Yang J, Zhang T, Li L, Wang F, Chen Z, Zheng T.   +7 more
europepmc   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida. [PDF]

Microbiologyopen
Bouras H, Quesnelle Y, Trancart S, Goux D, Blin JL, Savary M, Houssin M, Zatylny-Gaudin C.   +7 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Phenotypic and genomic characterization of <i>Castellaniella ginsengisoli</i>, an emerging pathogen associated with disease in birds. [PDF]

Microbiol Spectr
Luo Y-C, Allen T, Nicholds J, Ard M, Mortimer TD, Maboni G.   +5 more
europepmc   +1 more source