Results 201 to 210 of about 2,956,729 (308)

Genomic Characterization of Influenza B Victoria Lineage Viruses Circulating in Saudi Arabia During the 2024-2025 Season. [PDF]

J Med Virol
Alzahrani N, Alyami R, BuAli Z, Fallatah O, Zakri S, Alnujaim A, Bosaeed M, Abujamel T, Hashem AM, Johani SA.   +9 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Clinical and genomic characterization of <i>Staphylococcus argenteus</i> isolates from a tertiary hospital in Beijing. [PDF]

Front Microbiol
Tian D, Liu Y, Li Y, Chen D, Ju L, Lan H, Yang W, Zhao X, Wang P, Cao J.   +9 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Genomic characterization of ER-positive primary tumors and corresponding relapses identifies potentially targetable alterations. [PDF]

NPJ Breast Cancer
Schagerholm Stanev C, Robertson S, Toosi H, Sifakis EG, Lagergren J, Hartman J.   +5 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

First molecular detection and genomic characterization of West Nile virus associated with a naturally aborted sheep in Tunisia. [PDF]

Curr Res Parasitol Vector Borne Dis
Boughattas S, Ouni A, Ayouni K, Jlassi T, Bouattour A, Fares W, M'ghirbi Y.   +6 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Genomic characterization of UTUC [PDF]

Nature Reviews Urology, 2017
openaire   +1 more source

Genomic characterization of avian metapneumovirus subtypes A and B in United States poultry by targeted amplicon sequencing. [PDF]

Front Cell Infect Microbiol
Duhan N, Selim MH, Kada P, Luqman M, Temeeyasen G, Radhakrishnan J, Sharafeldin TA, Mor S.   +7 more
europepmc   +1 more source