Results 1 to 10 of about 1,426,096 (120)
Genetic dependency of Alzheimer’s disease-associated genes across cells and tissue types
Scientific Reports, 2021 Effective treatments targeting disease etiology are urgently needed for Alzheimer’s disease (AD). Although candidate AD genes have been identified and altering their levels may serve as therapeutic strategies, the consequence of such alterations remain ...
Suraj K. Jaladanki +3 more
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Integrative Analysis of Histopathological Images and Genomic Data in Colon Adenocarcinoma
Frontiers in Oncology, 2021 BackgroundColon adenocarcinoma (COAD) is one of the most common malignant tumors in the world. The histopathological features are crucial for the diagnosis, prognosis, and therapy of COAD.MethodsWe downloaded 719 whole-slide histopathological images from
Hui Li +10 more
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Detecting and phasing minor single-nucleotide variants from long-read sequencing data
Nature Communications, 2021 Cellular genetic heterogeneity is common across biological conditions, yet application of long-read sequencing to this subject is limited by error rates.
Zhixing Feng +3 more
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Frontiers in Genetics, 2023 In the last decade, a number of methods have been suggested to deal with large amounts of genetic data in genomic predictions. Yet, steadily growing population sizes and the suboptimal use of computational resources are pushing the practical application ...
Alexander Freudenberg +5 more
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Genome Biology, 2020 Non-canonical residues, caps, crosslinks, and nicks are important to many functions of DNAs, RNAs, proteins, and complexes. However, we do not fully understand how networks of such non-canonical macromolecules generate behavior.
Paul F. Lang +6 more
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DATA SCIENCE, CANCER AND SEQUENCING ANALYSES
Sabiad, 2022 Recent developments in technology led to exponential growth in processing speed, storage capacities and communication rates. These available resources allowed the creation of thousands of applications that run on smart devices and the world wide web ...
Mehmet Baysan
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Genomic structure of Bali cattle based on linkage disequilibrium and effective population size analyses using 50K single nucleotide polymorphisms data [PDF]
Veterinary World, 2022 Background and Aim: Bali Cattle (Bos j. javanicus) is a local breed originating in Indonesia, accounting for 32.3% of the total cattle population. To date, no studies of the genetic structure and demographic status of Bali cattle have been conducted ...
Pita Sudrajad +3 more
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Bayesian weighted random forest for classification of high-dimensional genomics data
Kuwait Journal of Science, 2023 In this paper, a full Bayesian weighted probabilistic model is developed for random classification trees. The new model Bayesian Weighted Random Classification Forest (BWRCF) arises from the modification of the existing random classification forest in ...
Oyebayo Ridwan Olaniran +1 more
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Predicting youth diabetes risk using NHANES data and machine learning
Scientific Reports, 2021 Prediabetes and diabetes mellitus (preDM/DM) have become alarmingly prevalent among youth in recent years. However, simple questionnaire-based screening tools to reliably assess diabetes risk are only available for adults, not youth.
Nita Vangeepuram +4 more
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Pan-cancer proteogenomic investigations identify post-transcriptional kinase targets
Communications Biology, 2021 Elmas et al. develop an algorithm, OPPTI, to identify overexpressed kinase proteins across 10 cancer types using global mass spectrometry proteomics data from over 1000 cases.
Abdulkadir Elmas +5 more
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