Results 41 to 50 of about 26,875,751 (309)
Integrated genome sizing (IGS) approach for the parallelization of whole genome analysis
BMC Bioinformatics, 2018 Background The use of whole genome sequence has increased recently with rapid progression of next-generation sequencing (NGS) technologies. However, storing raw sequence reads to perform large-scale genome analysis pose hardware challenges.
Peter Sona +13 more
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Frontiers in Oncology, 2023 BackgroundMetastatic breast cancer (mBC) causes nearly all BC-related deaths. Next-generation sequencing (NGS) technologies allow for the application of personalized medicine using targeted therapies that could improve patients’ outcomes. However, NGS is
Rubén Olivera-Salguero +69 more
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The future of legume genetic data resources: Challenges, opportunities, and priorities
, 2019 This article is a commentary on the future of legume genetic data resources and summarizes the workshop held in March of 2019 by the Legume Genomic Data Working Group that addressed questions of data resources and priorities for ...
Dickstein, Rebecca +1 more
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Large Language Models in Genomics—A Perspective on Personalized Medicine
BioengineeringIntegrating artificial intelligence (AI), particularly large language models (LLMs), into the healthcare industry is revolutionizing the field of medicine. LLMs possess the capability to analyze the scientific literature and genomic data by comprehending
Shahid Ali +7 more
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Genomic medicine and data sharing [PDF]
British Medical Bulletin, 2017 Effective data sharing does not occur in the UK despite being essential for the delivery of high-quality genomic services to patients across clinical specialities and to optimize advances in genomic medicine.Original papers, reviews, guidelines, policy papers and web-resources.Data sharing for genomic medicine requires appropriate infrastructure and ...
Sobia Raza, Alison Hall
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Accuracy of multi-trait genomic selection using different methods [PDF]
, 2011 Background Genomic selection has become a very important tool in animal genetics and is rapidly emerging in plant genetics. It holds the promise to be particularly beneficial to select for traits that are difficult or expensive to measure, such as traits
Veerkamp Roel F +5 more
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Biology, 2023 Deep learning has brought about a significant transformation in machine learning, leading to an array of novel methodologies and consequently broadening its influence.
Minhyeok Lee
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Trends in GeneticsMachine learning (ML) is developing into an inherent part of genomic research due to the ever-increasing amounts of genomic data. However, data-driven algorithms are strongly dependent on good quality and representative data, which can be problematic in genomics due to various reasons. One of these reasons is data biases-flawed or incomplete data often
Lusine Nazaretyan, Martin Kircher
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source