Results 61 to 70 of about 26,875,751 (309)

data for CasPER, a method for directed evolution in genomic contexts using mutagenesis and CRISPR/Cas9

open access: yes, 2018
This is the raw NGS sequencing data as python analysis for the paper thats currently titled: CasPER, a method for directed evolution in genomic contexts using mutagenesis and CRISPR ...
Pedersen, L (via Mendeley Data)   +1 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

FWAlgaeDB, an integrated genome database of freshwater algae

open access: yesFrontiers in Environmental Science, 2023
Algal genomics research contributes to a deeper understanding of algal evolution and provides useful genomics inferences correlated with various functions. Published algal genome sequences are very limited owing to genome assembly challenges.
Juan Lai   +18 more
doaj   +1 more source

Prosecutor: parameter-free inference of gene function for prokaryotes using DNA microarray data, genomic context and multiple gene annotation sources [PDF]

open access: yes, 2008
Background: Despite a plethora of functional genomic efforts, the function of many genes in sequenced genomes remains unknown. The increasing amount of microarray data for many species allows employing the guilt-by-association principle to predict ...
Hofstede, K.J.   +27 more
core   +1 more source

A pipeline for effectively developing highly polymorphic SSR markers based on multi-sample genomic data

open access: yes, 2022
Simple sequence repeats (SSRs) are widely used genetic markers in ecology, evolution and conservation even in the genomics era, while a general limitation to their application is the difficulty of developing polymorphic SSR markers.
Chen, D (via Mendeley Data), Chen, De
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Machine Learning for Genomic Data

open access: yesCoRR, 2021
This report explores the application of machine learning techniques on short timeseries gene expression data. Although standard machine learning algorithms work well on longer time-series', they often fail to find meaningful insights from fewer timepoints. In this report, we explore model-based clustering techniques.
openaire   +2 more sources

A genomic data viewer for iPad [PDF]

open access: yesGenome Biology, 2015
AbstractThe Integrative Genomics Viewer (IGV) for iPad, based on the popular IGV application for desktop and laptop computers, supports researchers who wish to take advantage of the mobility of today’s tablet computers to view genomic data and present findings to colleagues.
Thorvaldsdóttir, Helga   +3 more
openaire   +4 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Application of Genomic Data in Translational Medicine During the Big Data Era

open access: yesFrontiers in Bioscience-Landmark
Advances in gene sequencing technology and decreasing costs have resulted in a proliferation of genomic data as an integral component of big data. The availability of vast amounts of genomic data and more sophisticated genomic analysis techniques has ...
Yun Zhang   +4 more
doaj   +1 more source

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