Results 81 to 90 of about 26,875,751 (309)

Visual Exploration of Genomic Data [PDF]

open access: yes, 2007
In this study, we present methods for comparative visualization of DNA sequences in two dimensions. First, we illustrate a transformation of gene sequences into numerical trajectories. The trajectory visually captures the nucleotide content of each sequence, allowing for fast and easy visualization of long DNA sequences.
Michail Vlachos   +3 more
openaire   +2 more sources

Data quality in genomics and microarrays [PDF]

open access: yesNature Biotechnology, 2006
Objective quality control indices are needed to facilitate clinical implementation of DNA microarrays used in transcriptional profiling as well as other types of genomic analysis.
Hanlee, Ji, Ronald W, Davis
openaire   +2 more sources

A global network for investigating the genomic epidemiology of malaria.

open access: yes, 2008
Large-scale studies of genomic variation could assist efforts to eliminate malaria. But there are scientific, ethical and practical challenges to carrying out such studies in developing countries, where the burden of disease is greatest.
Malaria Genomic Epidemiology Network, Malaria Genomic Epidemiology
core   +1 more source

The TCGA cancer data for the paper entitled "Feature Screening for Survival Trait with Application to TCGA High-dimensional Genomic Data"

open access: yes, 2021
The TCGA ESCA, PAAD, LUAD, and BRCA genomic data with survival traits for the paper entitled "Feature Screening for Survival Trait with Application to TCGA High-dimensional Genomic Data".
Jie-Huei Wang (11421263)
core   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Identification of genes related to ketosis in dairy cows and establishment of early detection method for aryl hydrocarbon receptor gene

open access: yesFrontiers in Veterinary Science
IntroductionKetosis is a common metabolic disease in periparturient dairy cows. Monitoring and early warning based on blood indicators have become a key research focus in this field.
Yu Wang   +12 more
doaj   +1 more source

Fine-scale analysis of six beef cattle breeds revealed patterns of their genomic diversity

open access: yesItalian Journal of Animal Science, 2020
There has been a significant decrease in genetic diversity on a global scale for several livestock species, including beef cattle. Therefore, the aim of this study was to deliver fine-scale analysis of the genomic structure and to describe the diversity ...
Radovan Kasarda   +12 more
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Data for: Phylogenetic relationships and systematics of the Amazonian poison frog genus Ameerega using ultraconserved genomic elements

open access: yes, 2019
Supplemental data for the manuscript "Phylogenetic relationships and systematics of the Amazonian poison frog genus Ameerega using ultraconserved genomic elements".
Guillory, Wilson   +1 more
core   +1 more source

A quantitative account of genomic island acquisitions in prokaryotes [PDF]

open access: yes, 2011
Background Microbial genomes do not merely evolve through the slow accumulation of mutations, but also, and often more dramatically, by taking up new DNA in a process called horizontal gene transfer.
van Passel, Mark W. J.   +7 more
core   +2 more sources

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