Results 1 to 10 of about 3,983,651 (404)

Inhibition of the PCR by genomic DNA. [PDF]

open access: yesPLoS One, 2023
Aims qPCR, is widely used for quantifying minimal residual disease (MRD) and is conventionally performed according to guidelines proposed by the EuroMRD consortium. However it often fails when quantifying MRD levels below 10−4. By contrast, HAT-PCR, a recent modification designed to minimise false-positive results, can quantify MRD down to 10−6 ...
Latham S, Hughes E, Budgen B, Morley A.
europepmc   +4 more sources

An investigation into inter- and intragenomic variations of graphic genomic signatures [PDF]

open access: yesarXiv, 2015
We provide, on an extensive dataset and using several different distances, confirmation of the hypothesis that CGR patterns are preserved along a genomic DNA sequence, and are different for DNA sequences originating from genomes of different species.
Karamichalis, Rallis   +3 more
arxiv   +6 more sources

Reconsidering the significance of genomic word frequency [PDF]

open access: yesarXiv, 2006
We propose that the distribution of DNA words in genomic sequences can be primarily characterized by a double Pareto-lognormal distribution, which explains lognormal and power-law features found across all known genomes. Such a distribution may be the result of completely random sequence evolution by duplication processes.
Csűrös, Miklós   +2 more
arxiv   +5 more sources

Sequencing of Genomic DNA [PDF]

open access: yesBioTechniques, 1999
Ulrich Mahlknecht   +2 more
doaj   +4 more sources

Whole-Exome Sequencing Identifies a Novel POLG Frameshift Variant in an Adult Patient Presenting with Progressive External Ophthalmoplegia and Mitochondrial DNA Depletion

open access: yesCase Reports in Genetics, 2021
Mitochondrial DNA (mtDNA) depletion syndromes are a group of autosomal recessive disorders associated with a spectrum of clinical diseases, which include progressive external ophthalmoplegia (PEO).
Justin Kurtz   +4 more
doaj   +1 more source

Remodeling the genome with DNA twists [PDF]

open access: yesScience, 2019
Intricate protein machines repackage DNA to turn genes on and ...
Bowman, Gregory D., Deindl, Sebastian
openaire   +3 more sources

The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster. [PDF]

open access: yes, 2016
Despite decades of work, our understanding of the distribution of fitness effects of segregating genetic variants in natural populations remains largely incomplete. One form of selection that can maintain genetic variation is spatially varying selection,
Begun, David J   +3 more
core   +12 more sources

In Vitro Isolation and Molecular Characterization of Genomic DNA from Ancient Human Long and Hip Bones

open access: yesMAMC Journal of Medical Sciences, 2023
Background: A simple and effective modified ethanol precipitation-based protocol was described for the extraction of genomic DNA from ancient human bones.
Dinesh Kumar   +4 more
doaj   +1 more source

An alternative application of some SSR DNA markers in experimental mycology

open access: yesUkrainian Botanical Journal, 2023
The expediency of using unique SSR DNA-markers of Schizophyllum commune for population genetic assays in various fungal species has been demonstrated.
Boiko S.M.
doaj   +1 more source

Analysis of DNA isolated from different oil sources: problems and solution [PDF]

open access: yesIranian Journal of Veterinary Medicine, 2017
Background: One of the major aspects of traceability in food authenticity assessment is to explore practical methods to find the origin of food. Objective: The aim of the present study was to find a DNA based method for authentication and traceability ...
Parviz shayan   +6 more
doaj   +1 more source

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