Results 281 to 290 of about 3,454,386 (367)

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

Improved metagenome assemblies through selective enrichment of bacterial genomic DNA from eukaryotic host genomic DNA using ATAC-seq. [PDF]

Front Microbiol
Cantin LJ, Dunning Hotopp JC, Foster JM.
europepmc   +1 more source

Amplification‐Free, Sequencing‐Free, Detection of Viral RNAs with Variant Specification by Discrete Nanocounting

Advanced Functional Materials, EarlyView.
Integrating selective RNA shortcut, targeted gene isolation, and micro‐arrayed nanoimaging, the NanoPick‐array platform excels in detecting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at just 60 copies µL−1 and accurately differentiating variants at the single‐nucleotide level. It ensures 100% accuracy for samples with cycle threshold (
Zixun Wang, Xi Zhao, Wan‐Mui Chan, Xianglin Ji, Linfeng Huang, Xi Xie, Wei Li, Wenjun Zhang, Kelvin Kai‐Wang To, Peng Shi   +9 more
wiley   +1 more source

Cloning and nucleotide sequences of the complementary and genomic DNAs for the alkaline protease from Acremonium chrysogenum.

, 1991
Takao Isogai, Masafumi Fukagawa, Hitoshi Kojo, MASANOBU KOHSAKA, Hideyuki Aoki, Hiroshi Imanaka   +5 more
openalex   +3 more sources

Analyzing Cell-free Genomic DNA in Spent Culture Media: Noninvasive Insight into the Blastocysts. [PDF]

Glob Med Genet
Layek SS, Kanani S, Doultani S, Gohil T, Patil S, Sudhakar A, Raval KB, Kuppusamy K, Gorani S, Raj S, Sangameshwari R, Jadeja H, P MM.   +12 more
europepmc   +1 more source

Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics

Advanced Functional Materials, EarlyView.
Designer DNA Architecture‐templated Drug Conjugates (DDA‐DCs) are comprised of a DNA nanomaterial decorated with multiple drug‐loaded DNA aptamers. DDA‐DCs use a combination of multiple aptamer types, each recognizing a different membrane protein to achieve precise targeting of cancer cells.
Abhisek Dwivedy, Dhyanesh Baskaran, Gaurav Sharma, Wei Hong, Dhanush Gandavadi, Abhichart Krissanaprasit, Joonsu Han, Yusheng Liu, Zack Zimmers, Tshepo Mafokwane, Ichrak Hayah, Neha Chauhan, Mengxi Zheng, Sherwood Yao, Keith Fraser, John S. Decker, Xiaohe Jin, Hua Wang, Adam D. Friedman, Xing Wang   +19 more
wiley   +1 more source

A biospecies-derived genomic DNA hybrid gel electrolyte for electrochemical energy storage. [PDF]

PNAS Nexus
Mitta SB, Kim J, Rana HH, Kokkiligadda S, Lim YT, Bhang SH, Park HS, Um SH.   +7 more
europepmc   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Protocol for iterative enrichment of integrated sgRNAs via derivative CRISPR-Cas9 libraries from genomic DNA of sorted fixed cells. [PDF]

STAR Protoc
Ordóñez A, Ron D, Harding HP.
europepmc   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source