Results 21 to 30 of about 1,136,601 (292)
DNA methylation of cancer genome [PDF]
Birth Defects Research Part C: Embryo Today: Reviews, 2009 AbstractDNA methylation plays an important role in regulating normal development and carcinogenesis. Current understanding of the biological roles of DNA methylation is limited to its role in the regulation of gene transcription, genomic imprinting, genomic stability, and X chromosome inactivation.
Hoi-Hung, Cheung +3 more
openaire +2 more sources
Veterinární Medicína, 2016 : The objective of this study was to evaluate a combined antibiotic-enzyme therapy for Staphylococcus aureus mastitis and biofilm formation. A total of 141 cases of S.
B. Khoramian +6 more
doaj +1 more source
Spore PCR and qPCR Methods for Rapid Detection of Five Colletotrichum Species Responsible for Pepper Anthracnose in Korea [PDF]
Research in Plant DiseasePepper anthracnose, caused by Colletotrichum spp., leads to a decrease in the quantity of pepper fruit production. Molecular diagnosis is crucial for rapid identification of pathogens and determination of fungicide resistance.
Haejun Jeong +5 more
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BioTechniques, 2023 High-quality genomic DNA extraction is fundamental for the study of gene cloning and expression in plants. Therefore, this study evaluated several methods for extracting genomic DNA from shoots of four Dendrocalamus species to determine the optimal ...
Yingchun Ma +6 more
doaj +1 more source
Estimation of Pool Construction and Technical Error
Agriculture, 2021 Pooling animals with extreme phenotypes can improve the accuracy of genetic evaluation or provide genetic evaluation for novel traits at relatively low cost by exploiting large amounts of low-cost phenotypic data from animals in the commercial sector ...
John Keele +4 more
doaj +1 more source
OENO One, 1994 Une nouvelle technique de la biologie moléculaire, la réaction de polymérisation en chaine (PCR) permet l'identification des souches de levures de vinification.
Isabelle Masneuf-Pomarède +1 more
doaj +1 more source
Clinical consequences of BRCA2 hypomorphism
npj Breast Cancer, 2021 The tumor suppressor FANCD1/BRCA2 is crucial for DNA homologous recombination repair (HRR). BRCA2 biallelic pathogenic variants result in a severe form of Fanconi anemia (FA) syndrome, whereas monoallelic pathogenic variants cause mainly hereditary ...
Laia Castells-Roca +17 more
doaj +1 more source
Profiling genome-wide DNA methylation [PDF]
Epigenetics & Chromatin, 2016 DNA methylation is an epigenetic modification that plays an important role in regulating gene expression and therefore a broad range of biological processes and diseases. DNA methylation is tissue-specific, dynamic, sequence-context-dependent and trans-generationally heritable, and these complex patterns of methylation highlight the significance of ...
Yong, Wai-Shin +2 more
openaire +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Gut microbiome as a biomarker of cardiometabolic disorders
Annals of Agricultural and Environmental Medicine, 2017 Introduction and objective Cardiovascular diseases are the leading cause of death in Europe and worldwide. One of the most important risk factors for atherosclerosis are lipid metabolism disorders, in particular hipercholesterolaemia.
Anna Gózd-Barszczewska +4 more
doaj +1 more source