The complete mitochondrial genome of Cepola schlegelii from the East China Sea
Mitochondrial DNA. Part B. Resources, 2022 Cepola schlegelii (Bleeker 1854) belongs to the genus Cepola in the family Cepolidae and order Priacanthiformes. The complete mitochondrial genome of C. schlegelii was sequenced and analyzed by a high-throughput sequencing approach.
Panjiao Liang +5 more
doaj +1 more source
Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage. [PDF]
, 2016 The hormone estrogen (E2) binds the estrogen receptor to promote transcription of E2-responsive genes in the breast and other tissues. E2 also has links to genomic instability, and elevated E2 levels are tied to breast cancer.
Bocek, Michael +7 more
core +3 more sources
Universal and rapid salt-extraction of high quality genomic DNA for PCR-based techniques.
Nucleic Acids Research, 1997 A very simple, fast, universally applicable and reproducible method to extract high quality megabase genomic DNA from different organisms is described. We applied the same method to extract high quality complex genomic DNA from different tissues (wheat ...
S. Aljanabi, Iciar Martinez
semanticscholar +1 more source
Not seeing the genomes for the DNA [PDF]
Briefings in Functional Genomics, 2012 This Short Communication highlights the diversity of 'secondary' genome data (like mitochondrial and plastid genomes) that can be gleaned from next-generation sequencing projects, and encourages researchers to be mindful that these data are often as informative and useful as the 'primary' genome data.
openaire +3 more sources
eLife, 2014 Homologous recombination (HR)-mediated repair of DNA double-strand break (DSB)s is restricted to the post-replicative phases of the cell cycle. Initiation of HR in the G1 phase blocks non-homologous end joining (NHEJ) impairing DSB repair.
Young Eun Choi +6 more
doaj +1 more source
Contribution of DNA repair and cell cycle checkpoint arrest to the maintenance of genomic stability [PDF]
, 2006 DNA damage response mechanisms encompass pathways of DNA repair, cell cycle checkpoint arrest and apoptosis. Together, these mechanisms function to maintain genomic stability in the face of exogenous and endogenous DNA damage.
Ahnesorg +41 more
core +1 more source
A simple and rapid method for the preparation of plant genomic DNA for PCR analysis.
Nucleic Acids Research, 1991 The polymerase chain reaction (PCR) has revolutionised the rapid analysis of mammalian genomic DNA (1). However, PCR is less useful in the analysis of plant DNA due to the difficulties in extracting nucleic acids from limited amounts of plant tissue.
K. Edwards, C. Johnstone, C. Thompson
semanticscholar +1 more source
A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages [PDF]
, 2017 Macrophages produce genotoxic agents, such as reactive oxygen and nitrogen species, that kill invading pathogens. Here we show that these agents activate the DNA damage response (DDR) kinases ATM and DNA-PKcs through the generation of double stranded ...
Akira +67 more
core +3 more sources
Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
Nature Communications, 2017 Glutaminase inhibition (GLSi) has promising activity against certain cancers. Here, the authors show that GLSi has no effect on multiple mouse models of pancreatic cancer and characterize the metabolic pathways activated in response to GLSi whose ...
Douglas E. Biancur +12 more
doaj +1 more source
NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms
Haematologica, 2019 Ncoa4 mediates autophagic degradation of ferritin, the cytosolic iron storage complex, to maintain intracellular iron homeostasis. Recent evidence also supports a role for Ncoa4 in systemic iron homeostasis and erythropoiesis.
Naiara Santana-Codina +11 more
doaj +1 more source