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Repetitive DNA in eukaryotic genomes
Chromosome Research, 2015Repetitive DNA--sequence motifs repeated hundreds or thousands of times in the genome--makes up the major proportion of all the nuclear DNA in most eukaryotic genomes. However, the significance of repetitive DNA in the genome is not completely understood, and it has been considered to have both structural and functional roles, or perhaps even no ...
Ettore Olmo +2 more
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Current Protocols in Molecular Biology, 1987
AbstractGenomic DNA libraries are almost always screened by hybridization using a radioactive nucleic acid probe. Since this approach is essentially independent of a particular vector or type of target DNA, the main problem faced when considering creation of a genomic DNA library is simply generating a large enough number of recombinant DNA clones. The
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AbstractGenomic DNA libraries are almost always screened by hybridization using a radioactive nucleic acid probe. Since this approach is essentially independent of a particular vector or type of target DNA, the main problem faced when considering creation of a genomic DNA library is simply generating a large enough number of recombinant DNA clones. The
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1987
Within the scope of this laboratory guide it is impossible to give a full review of all the procedures used in the isolation of intact genomic DNA. However, we shall describe a general method we used which gives an excellent quality of both nuclei and DNA suitable for genomic sequencing.
Jean-Pierre Jost, Hanspeter Saluz
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Within the scope of this laboratory guide it is impossible to give a full review of all the procedures used in the isolation of intact genomic DNA. However, we shall describe a general method we used which gives an excellent quality of both nuclei and DNA suitable for genomic sequencing.
Jean-Pierre Jost, Hanspeter Saluz
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Analytical Chemistry, 2013
We report a method for the sensitive measurement of genomic DNA based on the direct detection of single molecules of DNA in arrays of femtoliter wells.
Linan Song +11 more
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We report a method for the sensitive measurement of genomic DNA based on the direct detection of single molecules of DNA in arrays of femtoliter wells.
Linan Song +11 more
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Genome Size of Mycoplasmal DNA
Nature, 1969ELECTRON microscopic studies of the contour length of DNA from a mycoplasma species, Mycoplasma hominis (H 39)1, have shown that the DNA in this organism is organized in a single circular chromosome, 262 microns long, corresponding to a molecular weight of 5.0 × 108 daltons.
A L Bak +3 more
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DNA Repeats in the Human Genome
1999Repetitive DNA sequences, interspersed throughout the human genome, are capable of forming a wide variety of unusual DNA structures with simple and complex loopfolding patterns. The hairpin formed by the fragile X repeat, (CCG)n, and the bipartite triplex formed by the Friedreich's ataxia repeat, (GAA)n/(TTC)n, show simple loopfolding.
S. V. Santhana Mariappan +4 more
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Symbiotic DNA in eukaryotic genomes
Trends in Ecology & Evolution, 1996The recent explosive growth of molecular genetic databases has yielded increasingly detailed insights into the evolutionary dynamics of eukaryotic genomes. DNA sequences with the self-encoded ability to transpose and replicate are unexpectedly abundant and widespread in eukaryotic genomes. They seem to be sexual parasites.
Graham Bell, Clifford Zeyl
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DNA clustering and genome complexity
Computational Biology and Chemistry, 2014Early global measures of genome complexity (power spectra, the analysis of fluctuations in DNA walks or compositional segmentation) uncovered a high degree of complexity in eukaryotic genome sequences. The main evolutionary mechanisms leading to increases in genome complexity (i.e.
Guillermo Barturen +5 more
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The Genomics of Plant Satellite DNA
2021The twenty-first century began with a certain indifference to the research of satellite DNA (satDNA). Neither genome sequencing projects were able to accurately encompass the study of satDNA nor classic methodologies were able to go further in undertaking a better comprehensive study of the whole set of satDNA sequences of a genome.
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Genome: twisting stories with DNA
Endeavour, 2013In 1920, the German botanist Hans Winkler coined the concept of the 'genome'. This paper explores the history of a concept that has developed in parallel with advances in biology and supports novel and powerful heuristic biological research in the 21st century.
Ricardo Noguera-Solano +2 more
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