Results 31 to 40 of about 305,884 (298)

Global genomic epidemiology of Streptococcus pyogenes

Infection, Genetics and Evolution, 2020
Streptococcus pyogenes is one of the Top 10 human infectious disease killers worldwide causing a range of clinical manifestations in humans. Colonizing a range of ecological niches within its sole host, the human, is key to the ability of this opportunistic pathogen to cause direct and post-infectious manifestations.
Jespersen, MG, Lacey, JA, Tong, SYC, Davies, MR   +3 more
openaire   +3 more sources

Progress and challenges in virus genomic epidemiology [PDF]

Trends in Parasitology, 2021
Genomic epidemiology, which links pathogen genomes with associated metadata to understand disease transmission, has become a key component of outbreak response. Decreasing costs of genome sequencing and increasing computational power provide opportunities to generate and analyse large viral genomic datasets that aim to uncover the spatial scales of ...
Verity Hill, Christopher Ruis, Sumali Bajaj, Oliver G. Pybus, Moritz U.G. Kraemer   +4 more
openaire   +2 more sources

Accessory Genomic Epidemiology of Cocirculating Acinetobacter baumannii Clones

mSystems, 2021
Whole-genome sequencing for epidemiological investigations (genomic epidemiology) has been of paramount importance to understand the transmission dynamics of many bacterial (and nonbacterial) pathogens.
Valeria Mateo-Estrada, José Luis Fernández-Vázquez, Julia Moreno-Manjón, Ismael L. Hernández-González, Eduardo Rodríguez-Noriega, Rayo Morfín-Otero, María Dolores Alcántar-Curiel, Santiago Castillo-Ramírez   +7 more
doaj   +1 more source

Monitoring genetic population biomarkers for wastewater-based epidemiology [PDF]

, 2017
We report a rapid “sample-to-answer” platform that can be used for the quantitative monitoring of genetic biomarkers within communities through the analysis of wastewater. The assay is based on the loop-mediated isothermal amplification (LAMP) of nucleic
Cooper, Jonathan M., Kasprzyk-Hordern, Barbara, Reboud, Julien, Xu, Gaolian, Yang, Zhugen   +4 more
core   +3 more sources

Genomic Epidemiology of Tuberculosis [PDF]

, 2017
The application of next generation sequencing technologies has opened the door to a new molecular epidemiology of tuberculosis, in which we can now look at transmission at a resolution not possible before. At the same time, new technical and analytical challenges have appeared, and we are still exploring the wider potential of this new technology ...
openaire   +3 more sources

Mutation of hilD in a Salmonella Derby lineage linked to swine adaptation and reduced risk to human health

Scientific Reports, 2020
Salmonella enterica variants exhibit diverse host adaptation, outcome of infection, and associated risk to food safety. Analysis of the distribution of Salmonella enterica serovar Derby (S.
Martina Tambassi, Melissa Berni, Chiara Bracchi, Erika Scaltriti, Marina Morganti, Luca Bolzoni, Jennifer R. Tanner, Gaëtan Thilliez, Robert A. Kingsley, Stefano Pongolini, Gabriele Casadei   +10 more
doaj   +1 more source

The Era of Genomic Epidemiology [PDF]

Neuroepidemiology, 2009
The recent revolution in genomics is already having a profound impact on the practice of epidemiology. The purpose of this commentary is to demonstrate how genomics and epidemiology will continue to rely heavily on each other, now and in the future, by illustrating a number of interaction points between these 2 disciplines: (1) the use of genomics to ...
openaire   +2 more sources

Robustness in quantifying the abundance of antimicrobial resistance genes in pooled faeces samples from batches of slaughter pigs using metagenomics analysis

Journal of Global Antimicrobial Resistance, 2021
Objectives: With the continued spread of antimicrobial resistance (AMR) in animals, it is important to assess its occurrence throughout a microbiome quantitatively in order to evaluate significantly affecting factors, e.g.
Vibe Dalhoff Andersen, Marie Stengaard Jensen, Patrick Munk, Håkan Vigre   +3 more
doaj   +1 more source

Genomic epidemiology of <i>Histoplasma</i> in Africa. [PDF]

mBio
ABSTRACT Histoplasmosis, the disease caused by thermally dimorphic fungi in the genus Histoplasma , is usually associated with pulmonary involvement in healthy individuals and a disseminated syndrome in immunocompromised patients. Among African patients, lung disease is less
Mapengo RE, Maphanga TG, Jofre GI, Rader JA, Turissini DA, Birkhead M, Kwabia SA, Sepúlveda VE, Buitrago MJ, Teixeira MdM, Barker BM, Alanio A, Sturny-Leclère A, Garcia-Hermoso D, Govender NP, Matute DR.   +15 more
europepmc   +3 more sources

Genetic determinants of cortical structure (thickness, surface area and volumes) among disease free adults in the CHARGE Consortium [PDF]

, 2019
Cortical thickness, surface area and volumes (MRI cortical measures) vary with age and cognitive function, and in neurological and psychiatric diseases.
Adams, H., Ahmad, S., Ames, D., Amin, N., Amouye, P., Andreassen, O., Armstrong, N., Bastin, M., Becker, J., Beiser, A., Bernard, M., Beyer, F., Bis, J., Bralten, J., Brodaty, H., Bülow, R., Carmichael, O., Colodro-Conde, L., Crivello, F., Dale, A., Deary, I., Debette, S., DeCarli, C., Fornage, M., Franz, C., Gillespie, N., Grabe, H., Grasby, K., Harris, M., Hibar, D., Himali, J., Hofer, E., Hofman, A., Ikram, M., Jahanshad, N., Jian, X., Jiang, J., Karama, S., Knol, M., Kremen, W., Kwok, J., Lewis, L., Li, S., Lin, H., Lind, P., Loeffler, M., Logue, M., Longstreth Jr., W., Lopez, O., Luciano, M., Lyons, M., Maillard, P., Maingault, S., Mather, K., Mazoyer, B., Medland, S., Mishra, A., Mosley, T., Neale, M., Niessen, W., Painter, J., Panizzon, M., Paus, T., Pausova, Z., Pike, G., Pirpamer, L., Pizzagalli, F., Psaty, B., Roshchupkin, G., Rotter, J., Saba, Y., Sachdev, P., Satizabal, C., Schmid, R., Schmidt, H., Schofield, P., Scholz, M., Seiler, S., Seshadr, S., Stein, J., Teumer, A., Thalamuthu, A., Thompson, P., Trollor, J., Tzourio, C., Uitterlinden, A., van der Lee, S., van Duijn, C., Vernooij, M., Villringer, A., Völker, U., Wardlaw, J., Wen, W., Witte, A., Wittfeld, K., Wright, M., Xia, R., Yang, Q., Zare, H.   +98 more
core   +2 more sources