Results 91 to 100 of about 22,903 (244)

Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle

BMC Genomics, 2018
Background While autozygosity as a consequence of selection is well understood, there is limited information on the ability of different methods to measure true inbreeding.
Mehrnush Forutan, Saeid Ansari Mahyari, Christine Baes, Nina Melzer, Flavio Schramm Schenkel, Mehdi Sargolzaei   +5 more
doaj   +1 more source

Captive Breeding of the Chinese Alligator Reduces Inbreeding but Increases Genetic Load

Integrative Zoology, EarlyView.
Captive breeding of the Chinese alligator successfully reduced genomic inbreeding but increased the burden of deleterious mutations. Genomic analyses indicate that managing both genetic diversity and genetic load is essential for the long‐term conservation of this critically endangered species.
Yihang Fan, Tao Pan, Nicolas Dussex, Tianming Lan   +3 more
wiley   +1 more source

Genomic Diversity of the Endangered Guinan Toad‐Headed Lizard and Its Conservation Implications

Integrative Zoology, EarlyView.
We produced HiFi long reads and assembled a high‐quality genome for the Guinan toad‐headed lizard—Phrynocephalus guinanensis—and present a comprehensive conservation genomics assessment. Our findings clearly show population structure, a reduced genetic diversity pattern, and a strong bottleneck in demographic history, reaffirming the endangered status ...
Ying Chen, Song Tan, Yiru Wang, Xia Qiu, Da Kang, Weizhao Yang   +5 more
wiley   +1 more source

From Evolutionary Genomics to Conservation Action: Gibbon as a System for Integrative Primate Genomics

Integrative Zoology, EarlyView.
This review synthesizes gibbon genomic research to propose a framework from evolutionary reconstruction and multidimensional vulnerability assessment to conservation intervention and long‐term dynamic monitoring. We clarify the supporting role of genomic evidence in conservation decision‐making and delineate a practicable pathway for integrating ...
Hangyu Tian, Pengfei Fan, Dongdong Wu
wiley   +1 more source

Genotyping Contemporary Captive and Historical Wild Western Lowland Gorillas Indicates Captive Breeding Is Maintaining Genetic Diversity in a Critically Endangered Primate

Animal Conservation, EarlyView.
Captive populations of threatened species risk losing genetic diversity over time. We evaluated the genetic status of contemporary captive western lowland gorillas (Gorilla gorilla gorilla) at Howletts and Port Lympne and compared this with specimens from a historical wild population.
Jaimie Morris, Tony King, John Hills, Simon C. Harvey, Jane Hopper, Rodrigo Vega   +5 more
wiley   +1 more source

Genomic Assessment of Reintroduced African Wild Dogs Informs Conservation Translocations

Animal Conservation, EarlyView.
Few reintroduction and translocation programs incorporate genomic assessments into management planning, despite ongoing debate over how founder individuals should be selected. Here, we assess the genomic composition of reintroduced African wild dog (Lycaon pictus) populations in private reserves in South Africa, comparing them with a free‐roaming ...
Michou Weimar, Cole du Plessis, Rosemary Groom, Bettine Jansen van Vuuren, Laura Tensen   +4 more
wiley   +1 more source

Genomic data illuminates demography, genetic structure and selection of a popular dog breed

BMC Genomics, 2017
Background Genomic methods have proved to be important tools in the analysis of genetic diversity across the range of species and can be used to reveal processes underlying both short- and long-term evolutionary change. This study applied genomic methods
Pamela Wiener, Enrique Sánchez-Molano, Dylan N. Clements, John A. Woolliams, Marie J. Haskell, Sarah C. Blott   +5 more
doaj   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

Advancing conservation breeding programs for marine invertebrates

Conservation Biology, EarlyView.
Abstract In the face of ecosystem change and biodiversity loss caused by climate change and other stressors, conservation breeding, or captive breeding, with the aim of reintroduction for wild population recovery, is an emerging tool for preventing species’ extinction and rehabilitating ecosystems.
Elora H. López‐Nandam, Bart Shepherd, Kylie Lev, Rebecca Albright   +3 more
wiley   +1 more source

Improved computation of genomic and pedigree inbreeding and relationships accounting for the X chromosome

Journal of Dairy Science
: Breeders for many decades used pedigrees to limit increases in inbreeding, but genomic measures of relationship and inbreeding provide more precise control.
Juan P. Nani, Gerald B. Jansen, Hafedh Ben Zaabza, Paul M. VanRaden   +3 more
doaj   +1 more source