Results 1 to 10 of about 167,442,745 (268)

Genomic runs of homozygosity record population history and consanguinity. [PDF]

PLoS ONE, 2010
The human genome is characterised by many runs of homozygous genotypes, where identical haplotypes were inherited from each parent. The length of each run is determined partly by the number of generations since the common ancestor: offspring of cousin ...
Mirna Kirin, Ruth McQuillan, Christopher S Franklin, Harry Campbell, Paul M McKeigue, James F Wilson   +5 more
doaj   +5 more sources

GENOMIC BACKGROUND OF ENTROPION IN FLECKVIEH CATTLE [PDF]

Poljoprivreda, 2015
Runs of homozygosity (ROH) and genome wide association study (GWAS) were used to identify genomic regions of entropion in Austrian Fleckvieh cattle. Entropion is an eye disorder where the eye lids turn inward, causing inflammations, cornea damage or even
Gábor Mészáros, Martin Peter Stückler , Maja Ferenčaković, Johann Sölkner   +3 more
doaj   +1 more source

Optimizing genetic diversity in Australian Holsteins and Jerseys: A comparative analysis of whole-genome and regional inbreeding depression effects

Journal of Dairy Science
: Homozygosity, which can arise from several genetic mechanisms including inbreeding, is frequently observed in the offspring of related parents. This inbreeding can lead to a reduced performance, owing to a phenomenon known as inbreeding depression ...
B.A. Scott, M. Haile-Mariam, F. Tiezzi, I. van den Berg, C. Maltecca, J.E. Pryce   +5 more
doaj   +1 more source

Genomic characterization of autozygosity and recent inbreeding trends in all major breeds of US dairy cattle

Journal of Dairy Science, 2022
: Maintaining a genetically diverse dairy cattle population is critical to preserving adaptability to future breeding goals and avoiding declines in fitness.
Emmanuel A. Lozada-Soto, Francesco Tiezzi, Jicai Jiang, John B. Cole, Paul M. VanRaden, Christian Maltecca   +5 more
doaj   +1 more source

Genome-wide detection for runs of homozygosity analysis in three pig breeds from Chinese Taihu Basin and Landrace pigs by SLAF-seq data

Journal of Integrative Agriculture, 2022
Erhualian (E), Meishan (MS) and Mi (MI) pigs are excellent indigenous pig breeds in Chinese Taihu Basin, which have made great contributions to the genetic improvement of commercial pigs. Investigation of the genetic structure and inbreeding level of the
Shi-feng TONG, Mo ZHU, Rui XIE, Dong-feng LI, Li-fan ZHANG, Yang LIU   +5 more
doaj   +1 more source

Inbreeding depression affecting stayability in Italian Holstein cows

Journal of Dairy Science
: Advances in selection and reproduction methods, particularly the implementation of genomic evaluations alongside assisted reproductive technologies, have substantially enhanced productivity and efficiency, notably within specialized dairy cattle ...
J.C.C. Panetto, C. Maltecca, M. Ablondi, S. Callegaro, J-T. van Kaam, R. Finocchiaro, A. Fabris, M.C. Fabbri, M. Cassandro, C. Cipolat-Gotet, A. Zanotti, R. Bozzi, F. Tiezzi   +12 more
doaj   +1 more source

Multi-trait meta-analyses reveal 25 quantitative trait loci for economically important traits in Brown Swiss cattle

BMC Genomics, 2019
Background Little is known about the genetic architecture of economically important traits in Brown Swiss cattle because only few genome-wide association studies (GWAS) have been carried out in this breed.
Zih-Hua Fang, Hubert Pausch
doaj   +1 more source

A high-density SNP array tailored for selectively bred Arctic charr (Salvelinus alpinus)

Aquaculture Reports
SNP arrays are indispensable tools for integrating genomic information into breeding programs. A SNP array for Nordic Arctic charr (Salvelinus alpinus) containing approximately 600,000 SNPs was developed from variants detected in Swedish, Norwegian and ...
Christos Palaiokostas, Martin Johnsson
doaj   +1 more source

Genomic dissection of inbreeding depression: a gate to new opportunities

Revista Brasileira de Zootecnia
Inbreeding depression, reduction in performance of quantitative traits, including reproduction and survival, caused by inbreeding, is a well-known phenomenon observed in almost all experimental, domesticated, and natural populations.
Ino Curik, Maja Ferenčaković, Johann Sölkner   +2 more
doaj   +1 more source

Using Runs of Homozygosity and Machine Learning to Disentangle Sources of Inbreeding and Infer Self-Fertilization Rates [PDF]

Genome Biology and Evolution
Leo Zeitler, Vincent Castric, Kimberly J Gilbert   +2 more
exaly   +2 more sources