Results 1 to 10 of about 7,051 (240)

Runs of Homozygosity Preliminary Investigation in Pig Breeds [PDF]

Animals
Runs of homozygosity (ROH) are contiguous homozygous genomic segments that provide valuable insights into population history, selection pressures, and inbreeding levels. However, the global distribution of ROH and their implications for pig domestication
Yuqiang Liu, Guangzhen Li, Wondossen Ayalew, Zhanming Zhong, Xiaohong Liu, Jiajie Sun, Jiaqi Li   +6 more
doaj   +4 more sources

Analysis of Runs of Homozygosity in Aberdeen Angus Cattle [PDF]

Animals
A large number of cattle breeds have marked phenotypic differences. They are valuable models for studying genome evolution. ROH analysis can facilitate the discovery of genomic regions that may explain phenotypic differences between breeds affecting ...
Vladimir Kolpakov, Alexey Ruchay, Dianna Kosyan, Elena Bukareva   +3 more
doaj   +4 more sources

Genomic Inbreeding and Runs of Homozygosity Analysis of Cashmere Goat [PDF]

Animals
Cashmere goats are valuable genetic resources which are famous worldwide for their high-quality fiber. Runs of homozygosity (ROHs) have been identified as an efficient tool to assess inbreeding level and identify related genes under selection.
Qian Zhao, Chang Huang, Qian Chen, Yingxiao Su, Yanjun Zhang, Ruijun Wang, Rui Su, Huijuan Xu, Shucai Liu, Yuehui Ma, Qianjun Zhao, Shaohui Ye   +11 more
doaj   +4 more sources

Inbreeding Calculated with Runs of Homozygosity Suggests Chromosome-Specific Inbreeding Depression Regions in Line 1 Hereford

Animals, 2021
The goal of this study was to evaluate inbreeding in a closed beef cattle population and assess phenotype prediction accuracy using inbreeding information.
Bethany Pilon, Kelly Hinterneder, El Hamidi A. Hay, Breno Fragomeni   +3 more
exaly   +3 more sources

Runs of homozygosity in Italian Holstein bulls: a permutation approach and time-based mapping of the genomic regions potentially under selection [PDF]

BMC Genomics
Background Runs of homozygosity (ROH) occurrence in animal genomes may result from a high level of relatedness within the population or from positive selection.
Laura Falchi, Alberto Cesarani, Luiz F. Brito, Salvatore Mastrangelo, Alfredo Pauciullo, Nicolò P. P. Macciotta, Giustino Gaspa   +6 more
doaj   +2 more sources

Genome-Wide Scan for Runs of Homozygosity Identifies Candidate Genes in Three Pig Breeds

Animals, 2019
Runs of homozygosity (ROH) are contiguous homozygous genotype segments in the genome that are present in an individual since the identical haplotypes are inherited from each parent.
Fuping Zhao, Liangyu Shi, Zhao Fuping
exaly   +3 more sources

Genomic inbreeding estimation in small populations: evaluation of runs of homozygosity in three local dairy cattle breeds

Animal, 2016
In the local breeds with small population size, one of the most important problems is the increase of inbreeding coefficient (F). High levels of inbreeding lead to reduced genetic diversity and inbreeding depression.
Salvatore Mastrangelo, Luca Fontanesi, Marco Tolone   +2 more
exaly   +3 more sources

Facial attractiveness is only weakly linked to genome–wide heterozygosity

Frontiers in Psychology, 2023
IntroductionIt has been frequently suggested that overall genomic heterozygosity and, particularly, heterozygosity of loci on the so-called major histocompatibility complex (MHC), which is responsible for the recognition of foreign substances/ pathogens ...
Martin Fieder, Martin Fieder, Susanne Huber   +2 more
doaj   +1 more source

Heterozygosity and homozygosity regions affect reproductive success and the loss of reproduction: A case study with litter traits in pigs

Computational and Structural Biotechnology Journal, 2022
Runs of heterozygosity (ROHet) and homozygosity (ROH) harbor useful information related to traits of interest. There is a lack of investigating the effect of ROHet and ROH on reproductive success and the loss of reproduction in mammals. Here, we detected
Zitao Chen, Zhenyang Zhang, Zhen Wang, Zhe Zhang, Qishan Wang, Yuchun Pan   +5 more
doaj   +1 more source

Correlation of Genomic and Pedigree Inbreeding Coefficients in Small Cattle Populations

Animals, 2021
This study aimed to identify inbreeding coefficient (F) estimators useful for improvement programs in a small Holstein population through the evaluation of different methodologies in the Mexican Holstein population.
José Cortes-Hernández, Adriana García-Ruiz, Carlos Gustavo Vásquez-Peláez, Felipe de Jesus Ruiz-Lopez   +3 more
doaj   +1 more source