Results 131 to 140 of about 1,126,913 (153)

Genomic instability — an evolving hallmark of cancer

open access: yesNature Reviews Molecular Cell Biology, 2010
Genomic instability is a characteristic of most cancers. In hereditary cancers, genomic instability results from mutations in DNA repair genes and drives cancer development, as predicted by the mutator hypothesis. In sporadic (non-hereditary) cancers the
Thanos Halazonetis, Vassilis Gorgoulis
exaly   +4 more sources

MicroRNAs, Genomic Instability and Cancer [PDF]

open access: yesInternational Journal of Molecular Sciences, 2014
MicroRNAs (miRNAs) are small non-coding RNA transcripts approximately 20 nucleotides in length that regulate expression of protein-coding genes via complementary binding mechanisms.
Gyeong-Won Lee   +2 more
exaly   +2 more sources

Genomic Instability and Epigenetic Changes during Aging

International Journal of Molecular Sciences, 2023
Amparo Pascual-Ahuir, Markus Proft
exaly  

miRNA dysregulation is an emerging modulator of genomic instability

Seminars in Cancer Biology, 2021
Ana Ferragut Cardoso   +2 more
exaly  

Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders

Cell, 2022
David S Gordon   +2 more
exaly  

Genomic Instability in Multiple Myeloma

Trends in Cancer, 2020
Robert Shmookler Reis   +2 more
exaly  

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