Results 171 to 180 of about 596,095 (346)

Genomic characterization of Helicobacter hepaticus: ordered cosmid library and comparative sequence analysis [PDF]

, 2001
Zhongming Ge
openalex   +1 more source

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

Advanced Materials, EarlyView.
Base editing using nanoneedles efficiently corrects pathogenic variants in the type VII collagen gene of primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. Nanoneedle editing induces minimal and reversible transcriptional perturbations while restoring the production and secretion of functional type VII collagen.
Salman Ahmad Mustfa, Marija Dimitrievska, Cong Wang, Chenlei Gu, Ningjia Sun, Katarzyna Romańczuk, Pawel Karpinski, Łukasz Łaczmański, John A. McGrath, Joanna Jacków‐Malinowska, Ciro Chiappini   +10 more
wiley   +1 more source

Efficient selection of genomic clones from a female chicken bacterial artificial chromosome library by four-dimensional polymerase chain reactions [PDF]

, 2002
Jyoji Kato, Takashi Hattori, Shinya Ohba, Y Tamaki, Nozomi Yamada, Tomoaki Taguchi, Jun Ogihara, Ken‐ichi Ohya, Yuichiro Itoh, Tetsuya Hori, Shuichi Asakawa, Nobutaka Shimizu, Shigeki Mizuno   +12 more
openalex   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

Bacteriophage Lambda Genomic Library Construction of Oryza sativa L. var. Pokkali

, 1970
Suhaila Rahman, Masa‐aki Ohto, Zeba I. Seraj, Eduardo Blumwald   +3 more
openalex   +2 more sources

PCR-Based Ordered Genomic Libraries: a New Approach to Drug Target Identification for Streptococcus pneumoniae [PDF]

, 2002
Aimee E. Belanger, Angel Lai, Marcia A. Brackman, Donald J. LeBlanc   +3 more
openalex   +1 more source

Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice‐Switching Oligonucleotides

Advanced Materials, EarlyView.
Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu, Hanna M. G. Barriga, Margaret N. Holme, Stefanie Morf, James J. Doutch, Samir EL Andaloussi, Tomas Kjellman, Markus Johnsson, Justas Barauskas, Molly M. Stevens   +9 more
wiley   +1 more source

Characterization of new Schistosoma mansoni microsatellite loci in sequences obtained from public DNA databases and microsatellite enriched genomic libraries [PDF]

, 2002
N. B. Rodrigues, PT LoVerde, AJ Romanha, Guilherme Oliveira   +3 more
openalex   +1 more source

Unlocking Multimodal Nonlinear Microscopy for Deep‐Tissue Imaging under Continuous‐Wave Excitation with Tunable Upconverting Nanoparticles

Advanced Materials, EarlyView.
This study introduces a multimodal nonlinear microscopy approach using upconverting nanoparticles (UCNPs) under continuous‐wave excitation. The UCNPs exhibit high‐order nonlinear optical responses, enabling deep‐tissue 3D imaging, video‐rate wide‐field imaging, and depth‐selective photomodulation.
Jeongmo Kim, Seunghun Lee, Yundon Jeong, Kyunghwan Kim, Kibum Nam, Hyungwon Jin, Yuha Choi, Hyun‐Jin Kim, Heungjin Ryu, Ki Hean Kim, Jae‐Ick Kim, Jongnam Park, Jinmyoung Joo, Jung‐Hoon Park   +13 more
wiley   +1 more source

Isolation and chromosomal localization of unique DNA sequences from a human genomic library.

, 1982
Fa‐Ten Kao, Judith A. Hartz, M L Law, Jeffrey N. Davidson   +3 more
openalex   +1 more source