Results 231 to 240 of about 596,095 (346)

Growth of a Saccharomyces cerevisiae strain lacking hexose transporters in different sugars after transformation with a Scheffersomyces stipitis genomic library [PDF]

, 2014
Belisa Bordin de Sales, Davi Gonçalves, Bruna Scheid, Boris U. Stambuk   +3 more
openalex   +1 more source

Loss of Golga7 Suppresses Oncogenic Nras‐Driven Leukemogenesis without Detectable Toxicity in Adult Mice

Advanced Science, EarlyView.
NRAS mutations are widespread in hematologic malignancies. Our study shows that GOLGA7 serves as a safe and effective therapeutic target for NRAS‐driven leukemia. Loss of Golga7 in adult mice effectively suppresses NrasG12D‐driven myeloproliferative neoplasm by disrupting its PM localization and impairing subsequent MAPK signaling, without affecting ...
Bo Jiao, Lei Yan, Rui Zhang, Wei Huang, Xinru Wang, Chenxuan Liu, Peihong Wang, Pengfei Xu, Jinzeng Wang, Zhou Fang, Donghe Li, Zhizhou Xia, Jiaoyang Li, Shiyu Ji, Qianqian Zhang, Min Wu, Shengyue Wang, Ping Liu, Ruibao Ren   +18 more
wiley   +1 more source

Subtelomeric repeat expansion in Hydractinia symbiolongicarpus chromosomes. [PDF]

Mob DNA
Kon T, Kon-Nanjo K, Simakov O.
europepmc   +1 more source

New strategy for Pinus pinaster genomic library construction in bacterial artificial chromosomes

, 2008
Rocí­o Bautista, David P. Villalobos, Sara M. Díaz-Moreno, Francisco R. Cantón, Francisco M. Cánovas, M. Gonzalo Claro   +5 more
openalex   +2 more sources

Expression of heterologous sigma factors enables functional screening of metagenomic and heterologous genomic libraries [PDF]

, 2015
Stefan M. Gaida, Nicholas R. Sandoval, Savvas Nicolaou, Yili Chen, Keerthi P. Venkataramanan, Eleftherios T. Papoutsakis   +5 more
openalex   +1 more source

Leveraging Automated Machine Learning for Environmental Data‐Driven Genetic Analysis and Genomic Prediction in Maize Hybrids

Advanced Science, EarlyView.
An automated machine learning framework integrating environmental and genomic data enhances genetic analysis and genomic prediction in maize. By leveraging dimension‐reduced environmental parameters, it reveals trait‐environment relationships and identifies genetic markers that govern phenotypic plasticity and genotype‐by‐environment interactions.
Kunhui He, Tingxi Yu, Shang Gao, Shoukun Chen, Liang Li, Xuecai Zhang, Changling Huang, Yunbi Xu, Jiankang Wang, Boddupalli M. Prasanna, Sarah Hearne, Xinhai Li, Huihui Li   +12 more
wiley   +1 more source

Polygenic Inheritance for Common Comorbidities Associated With Congenital Heart Disease. [PDF]

JACC Adv
Thompson JM, Tarr IS, Rath EM, Troup M, Ip EKK, Congenital Heart Disease Synergy Study Group, Blue GM, Winlaw DS, Dunwoodie SL, Giannoulatou E.   +9 more
europepmc   +1 more source

Generation of a pooled shRNA library for functional genomics screens

, 2022
Dimitrios Papadopoulos, Carsten P. Ade, Martin Eilers   +2 more
openalex   +1 more source

DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection

Advanced Science, EarlyView.
DPImpute is a two‐step pipeline that outperforms existing tools in whole‐genome SNP imputation, particularly under conditions of ultra‐low coverage sequencing, small sample sizes, and limited references. It enables precise imputation for single blastocyst cells, supporting genomic selection at the pre‐implantation stage.
Weigang Zheng, Wenlong Ma, Zhilong Chen, Chao Wang, Tao Sun, Wenjun Dong, Wenjing Zhang, Song Zhang, Zhonglin Tang, Kui Li, Yunxiang Zhao, Yuwen Liu   +11 more
wiley   +1 more source

ChIPbinner: an R package for analyzing broad histone marks binned in uniform windows from ChIP-Seq or CUT&RUN/TAG data. [PDF]

BMC Bioinformatics
Padilla R, Bareke E, Hu B, Majewski J.
europepmc   +1 more source