Results 261 to 270 of about 633,728 (345)

Complete genome sequence of <i>Bradyrhizobium japonicum</i> ACCC 15027. [PDF]

Microbiol Resour Announc
Zhang Y, Zou G, Li C, Yan Y, Lin M, Zhan Y.   +5 more
europepmc   +1 more source

High-throughput Functional Genomic Screening using Saturating Transposon Mutant Libraries and Next Generation Sequencing in Rhizobium leguminosarum

, 2015
Benjamin J. Perry
openalex   +1 more source

Contribution of user-prepared next-generation sequencing libraries to overall sample pool in the Genomics Core.

Jaroslav Zak (652743), Ian Newman (14794720), Daniel J. Montiel Garcia (22226914), Daniele Parisi (4557619), Janet Joy (22226917), Steven R. Head (22226920), Jean-Christophe Ducom (3565817), Padmaja Natarajan (61227), Haissi Cui (12001301), Sabah Ul-Hasan (4455052)   +9 more
openalex   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

A chromosome-level genome assembly for the brown sea cucumber from the Galápagos Islands, Isostichopus fuscus. [PDF]

Sci Data
Ortiz-Pachar JD, Ramírez-González J, Moity N, Andrade-Vera S, Rivadeneira WD, Therkildsen NO.   +5 more
europepmc   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Genome sequence of <i>Paenibacillus</i> sp. M.A.Huq-84 isolated from the rhizosphere of pine tree located in Anseong, South Korea. [PDF]

Microbiol Resour Announc
Huq MA, Kang K-K, Rahman MM.
europepmc   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Optimized DNA affinity purification sequencing determines relative binding affinity of transcription factors. [PDF]

Biol Methods Protoc
Schiller K, Meierhenrich A, Zenker S, Sielmann LM, Laker B, Bräutigam A.   +5 more
europepmc   +1 more source