Results 21 to 30 of about 596,095 (346)
The Sleipnir library for computational functional genomics [PDF]
Bioinformatics, 2008 Abstract Motivation: Biological data generation has accelerated to the point where hundreds or thousands of whole-genome datasets of various types are available for many model organisms. This wealth of data can lead to valuable biological insights when analyzed in an integrated manner, but the computational challenge of managing such ...
Maria Chikina +3 more
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Efficient Generation of Genome-wide Libraries for Protein–ligand Screens Using Gibson Assembly
Bio-Protocol, 2022 Genome-wide screens using yeast or phage displays are powerful tools for identifying protein–ligand interactions, including drug or vaccine targets, ligand receptors, or protein–protein interactions.
Tamara Sternlieb +3 more
doaj +1 more source
Implementation Science, 2021 Background Numerous implementation strategies to improve utilization of statins in patients with hypercholesterolemia have been utilized, with varying degrees of success.
Laney K. Jones +13 more
doaj +1 more source
Biases in the SMART-DNA library preparation method associated with genomic poly dA/dT sequences. [PDF]
PLoS ONE, 2017 Avoiding biases in next generation sequencing (NGS) library preparation is crucial for obtaining reliable sequencing data. Recently, a new library preparation method has been introduced which has eliminated the need for the ligation step.
Oriya Vardi +4 more
doaj +1 more source
SODA: a TypeScript/JavaScript Library for Visualizing Biological Sequence Annotation [PDF]
, 2022 We present SODA, a lightweight and open-source visualization library for biological sequence annotations that enables straightforward development of flexible, dynamic, and interactive web graphics. SODA is implemented in TypeScript and can be used as a library within TypeScript and JavaScript.
arxiv +1 more source
Optimization of high molecular weight DNA extraction methods in shrimp for a long-read sequencing platform [PDF]
PeerJ, 2020 Marine organisms are important to global food security as they are the largest source of animal proteins feeding mankind. Genomics-assisted aquaculture can increase yield while preserving the environment to ensure sufficient and sustainable production ...
Pacharaporn Angthong +11 more
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Molecular Plant-Microbe Interactions, 2000 A resistance (R) gene-rich 2S chromosomal segment from Triticum ventricosum contains a cereal cyst nematode (CCN; Heterodera avenae) R gene locus CreX and a closely linked group of genes (Sr38, Yr17, and Lr37) that confer resistance to stem rust ...
S. Seah +4 more
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Test: Construction of genomic libraries [PDF]
Biochemistry and Molecular Biology Education, 2005 AbstractTerms to be familiar with before you start to solve the test: genomic library, gel filtration, restriction endonuclease, plasmid, sticky ends, blunt ends, ligation, recombinant DNA, bacterium transformation, denaturation and renaturation of DNA, satellite DNA, telomere, centromere, unique and repetitive sequences.
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Exome sequencing from nanogram amounts of starting DNA: comparing three approaches. [PDF]
PLoS ONE, 2014 Hybridization-based target enrichment protocols require relatively large starting amounts of genomic DNA, which is not always available. Here, we tested three approaches to pre-capture library preparation starting from 10 ng of genomic DNA: (i and ii ...
Vera N Rykalina +5 more
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GENOME: A GENeric methodology for Ontological Modelling of Epics [PDF]
, 2022 Ontological knowledge modelling of epics, though being an established research arena backed by concrete multilingual and multicultural works, still suffer from two key shortcomings. Firstly, all epic ontological models developed till date have been designed following ad-hoc methodologies, most often, combining existing general purpose ontology ...
arxiv +1 more source