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Paternal Obesity‐Induced H3K27me3 Elevation Leads to MANF‐Mediated Transgenerational Metabolic Dysfunction in Female Offspring

open access: yesAdvanced Science, EarlyView.
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi   +13 more
wiley   +1 more source

Haplotype-resolved genomes of Trichophyton mentagrophytes and Trichophyton tonsurans. [PDF]

open access: yesSci Data
Feng S   +7 more
europepmc   +1 more source

Structural variant and nucleosome occupancy dynamics postchemotherapy in a HER2+ breast cancer organoid model. [PDF]

open access: yesProc Natl Acad Sci U S A
Starostecka M   +9 more
europepmc   +1 more source
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Screening of Genomic Libraries

2013
Microsatellites, or simple sequence repeats (SSRs), have proven to be an important molecular marker in plant genetics and breeding research. The main strategies to obtain these markers can be through genomic DNA and from expressed sequence tags (ESTs) from mRNA/cDNA libraries.
Novelli, Valdenice M.   +4 more
openaire   +4 more sources

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