Results 191 to 200 of about 536,771 (324)

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Obscured-ensemble models for genomic prediction. [PDF]

PLoS One
Saha R, Morshedian A, Sun J, Duncan R, Domaratzki M.   +4 more
europepmc   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Genomic prediction powered by multi-omics data. [PDF]

Front Genet
Montesinos-López OA, Montesinos-López A, Mosqueda-González BA, Delgado-Enciso I, Chavira-Flores M, Crossa J, Dreisigacker S, Sun J, Ortiz R.   +8 more
europepmc   +1 more source

A zero altered Poisson random forest model for genomic-enabled prediction

, 2020
Osval A. Montesinos‐López, Abelardo Montesinos‐López, B. González, J. Cricelio Montesinos-López, José Crossa, Nerida Lozano Ramirez, P. K. Singh, Felícitas Alejandra Valladares-Anguiano   +7 more
openalex   +1 more source

Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow, Matthew Katz, Jonathan Rodgers, Mark Davis, Thomas Robertson, R. J. McKinlay Gardner, Pamela A. McCombe   +6 more
wiley   +1 more source

Genomic prediction and association mapping of early season flood tolerance in soybean. [PDF]

Plant Genome
Vieira CC, Wu C, Harrison D, Marmo R, Florez-Palacios L, Acuna A, Rogers D, Fernandes SB, Fernandes I, Shannon G, Ye H, Nguyen HT.   +11 more
europepmc   +1 more source

MOESM1 of Genome-wide association and genomic prediction of resistance to viral nervous necrosis in European sea bass (Dicentrarchus labrax) using RAD sequencing

, 2018
Christos Palaiokostas, Sophie Cariou, Anastasia Bestin, Jean-Sébastien Bruant, Pierrick Haffray, Thierry Morin, JoĂŤlle Cabon, FrançOis Allal, Marc Vandeputte, Ross D. Houston   +9 more
openalex   +1 more source

Prediction of Ischemic Events on the Basis of Transcriptomic and Genomic Profiling in Patients Undergoing Carotid Endarterectomy [PDF]

, 2012
Lasse Folkersen, Jonas Persson, Johan Ekstrand, Hanna E. Agardh, Göran K. Hansson, Anders Gabrielsen, Ulf Hedin, Gabrielle Paulsson‐Berne   +7 more
openalex   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source