Results 191 to 200 of about 301,899 (294)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Harnessing genomic prediction in Brassica napus through a nested association mapping population. [PDF]

Plant Genome
Perumal S, Higgins EE, Sra S, Khedikar Y, Moore J, Chaudary R, Haile T, Koh CS, Vail S, Robinson SJ, Horner K, Hope B, Klein-Gebbinck H, Herrmann DT, Navabi K, Sharpe AG, Parkin IAP.   +16 more
europepmc   +1 more source

A foundational model for joint sequence-function multi-species modeling at scale for long-range genomic prediction

Sam Boshar, Benjamin Evans, Ziqi Tang, Armand Picard, Yanis Adel, Franziska K. Lorbeer, Chandana Rajesh, Tristan Karch, Shawn Sidbon, David Emms, Javier Mendoza-Revilla, Fatimah Al-Ani, Evan Seitz, Yair Schiff, Yohan Bornachot, Ariana Hernandez, Marie Lopez, Alexandre Laterre, Karim Beguir, Peter K. Koo, Volodymyr Kuleshov, Alex Stark, Bernardo P. de Almeida, Thomas Pierrot   +23 more
openalex   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Genomic prediction for heat and herbicide tolerance in faba bean. [PDF]

Plant Genome
Abou Khater L, Joukhadar R, Maalouf F, Alsamman AM, Babiker Z, Balech R, Hu J, Ma Y, Dunham A, Sanchez M, Jighly A, Kumar S, Kumar S.   +12 more
europepmc   +1 more source

DIGRE: Drug‐Induced Genomic Residual Effect Model for Successful Prediction of Multidrug Effects [PDF]

, 2015
Jichen Yang, Jing Tang, Yunguo Li, Rui Zhong, Tsung-Ming Wang, STC Wong, Guanghua Xiao, Yang Xie   +7 more
openalex   +1 more source

Validation of a Genetic Risk Score Combined with Clinical Variables for Predicting Pulmonary Fibrosis in early Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objectives Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). The study aimed to externally validate a genetic risk score (GRS) and a combined risk score for predicting the risk of RA‐associated PF in an independent cohort of early‐RA patients. Methods This study utilized an inception cohort of 1118 patients
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Boosting Genomic Prediction Transferability with Sparse Testing. [PDF]

Genes (Basel)
Montesinos-López OA, Crossa J, Vitale P, Gerard G, Crespo-Herrera L, Dreisigacker S, Saint Pierre C, Delgado-Enciso I, Montesinos-López A, Howard R.   +9 more
europepmc   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source

Genomic Predictions of Genotype x Environment interactions using weather data in wheat (Triticum aestivum L.)

, 2016
Delphine Ly
openalex   +1 more source