Results 211 to 220 of about 616,505 (302)

Genomic selection accuracy and bias using imputed genotypes on growth, welfare and fitness traits in two Pekin duck lines. [PDF]

BMC Genomics
Matika O, Tarsani E, McIntosh K, Kebede FG, Talenti A, Rae AM, Kranis A, Watson KA.   +7 more
europepmc   +2 more sources

PeachDB: accelerating breeding by reducing cost with AI-powered genomic selection in peach. [PDF]

Hortic Res
Han Q, Lou Y, Zhu T, Jin H, Zhang L, Zhang B.   +5 more
europepmc   +1 more source

Genomic selection: promises and propriety [PDF]

Journal of Animal Breeding and Genetics, 2010
openaire   +2 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The Establishment of a Sheep Embryo Genomic Selection System. [PDF]

Int J Mol Sci
Wang Y, Qin H, Li K, Hao J, Liu X, Chen D, Cheng L, He H, Wu R, Wu Y, Wang Y, Guo M, Li Q, An L, Tian J, Han H, Xi G.   +16 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

GS4PB: An R Shiny application to facilitate a genomic selection pipeline for plant breeding. [PDF]

Plant Genome
Ramasubramanian V, Wartha CA, Singh L, Vitale P, Ru S, Bhusal SJ, Lorenz AJ.   +6 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Normalized cumulative gain as an alternative evaluation measure for genomic selection models. [PDF]

Genet Sel Evol
Heinrich F, Lange TM, Ramzan F, Gültas M, Schmitt AO.   +4 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source