Results 251 to 260 of about 984,187 (300)

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Optimizing genomic selection models for wheat breeding under contrasting water regimes in a mediterranean environment. [PDF]

Plant Methods
Yannam VRR, Lopes MS, Soriano JM.
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Genomic selection and reproducibility: are complex models distracting us from true scientific validity in the presence of genotype-by-environment interaction? [PDF]

G3 (Bethesda)
Howard R, Lipka AE.
europepmc   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Assessment of the potential for genomic selection to improve resistance to fusarium stalk rot in maize. [PDF]

Front Plant Sci
Lohithaswa HC, Showkath Babu BM, Sowmya MS, Banakar SK, Mallikarjuna N, Jadesha G, Mallikarjuna MG, Balasundara DC, Anand P.   +8 more
europepmc   +1 more source

Genomic selection of maize test-cross hybrids leveraged by marker sampling. [PDF]

Plant Genome
Bernardeli A, Guilhen JHS, Oliveira ICM, Guimarães LJM, Borém A, Jarquin D, Pastina MM.   +6 more
europepmc   +1 more source

Optimizing progeny size and number of crosses under genomic selection: insights into additive and epistatic contributions to long-term genetic gain. [PDF]

Theor Appl Genet
da Silva Viana J, DoVale JC, Fritsche-Neto R.   +2 more
europepmc   +1 more source

Analysis of genomic selection characteristics of local cattle breeds in Gansu. [PDF]

BMC Genomics
Cai B, Kang Y, Xiong L, Pei J, Ge Q, Wu X, Gan M, Guo X.   +7 more
europepmc   +1 more source

Genomic Selection for Economic Traits in Inner Mongolia Cashmere Goats by Integrating GWAS Prior Information. [PDF]

Vet Sci
Xi H, Xu Q, Yao H, Shen Z, Zhou B, Lv Q, Li J, Wang R, Zhang Y, Su R, Wang Z.   +10 more
europepmc   +1 more source