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Diversifying maize genomic selection models
Molecular Breeding, 2021Genomic selection (GS) is one of the most powerful tools available for maize breeding. Its use of genome-wide marker data to estimate breeding values translates to increased genetic gains with fewer breeding cycles. In this review, we cover the history of GS and highlight particular milestones during its adaptation to maize breeding.
Brian R. Rice, Alexander E. Lipka
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Inbreeding in genome‐wide selection
Journal of Animal Breeding and Genetics, 2007SummaryTraditional selection methods, such as sib and best linear unbiased prediction (BLUP) selection, which increased genetic gain by increasing accuracy of evaluation have also led to an increased rate of inbreeding per generation (ΔFG). This is not necessarily the case with genome‐wide selection, which also increases genetic gain by increasing ...
Daetwyler, H.D. +3 more
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Genomic Selection in Aquaculture Species
2022To date, genomic prediction has been conducted in about 20 aquaculture species, with a preference for intra-family genomic selection (GS). For every trait under GS, the increase in accuracy obtained by genomic estimated breeding values instead of classical pedigree-based estimation of breeding values is very important in aquaculture species ranging ...
François, Allal, Nguyen Hong, Nguyen
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Selection still shapes our genome
Nature Human Behaviour, 2021A key question in human evolutionary genetics is whether and how natural selection has shaped the human genome. A new study by Song and colleagues uses GWAS data to examine evidence for the effects of polygenic adaptation in complex traits at different time scales.
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Genomic Selection in Plant Breeding
2014Genomic selection (GS) is a method to predict the genetic value of selection candidates based on the genomic estimated breeding value (GEBV) predicted from high-density markers positioned throughout the genome. Unlike marker-assisted selection, the GEBV is based on all markers including both minor and major marker effects.
Mark A, Newell, Jean-Luc, Jannink
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Genomic insights into positive selection
Trends in Genetics, 2006The traditional way of identifying targets of adaptive evolution has been to study a few loci that one hypothesizes a priori to have been under selection. This approach is complicated because of the confounding effects that population demographic history and selection have on patterns of DNA sequence variation.
Shameek, Biswas, Joshua M, Akey
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How retroviruses select their genomes
Nature Reviews Microbiology, 2005As retroviruses assemble in infected cells, two copies of their full-length, unspliced RNA genomes are selected for packaging from a cellular milieu that contains a substantial excess of non-viral and spliced viral RNAs. Understanding the molecular details of genome packaging is important for the development of new antiviral strategies and to enhance ...
Victoria, D'Souza, Michael F, Summers
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Pathogens select for genomic variants
Science, 2017Malarial Genomics Large-scale deletions and duplications of genes, referred to as structural variants (SVs), are common within the human genome and have been linked to disease. Examining a genomic region that appears to confer a selective benefit, Leffler et al.
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Genomic selection in hybrid breeding
Plant Breeding, 2014AbstractWhile hybrid breeding is widely applied in outbreeding species, for many self‐pollinating crop plants, it has only recently been established. This may have had its reason in the limitations of methods available for hybrid performance prediction, in particular when established heterotic pools were absent.
Albert Wilhelm Schulthess +2 more
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