Results 201 to 210 of about 3,072,702 (307)

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source

Reactive Oxygen Species: Molecular Mechanisms, Cellular Targets, and Implications for Genomic Stability. [PDF]

Biomed Res Int
Aziz A, Wissam Z.
europepmc   +1 more source

Discussion paper: the German Turkey debate under the grand coalition / European Stability Initiative

, 2006
unknown
core   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Folic acid prevents inner hair cell degeneration via genomic stability. [PDF]

Cell Death Discov
Cai R, Ma X, Lu J, Liu H, Wang M, Wang Z, Xi Q, Wu H, Zhang Z, Liu H.   +9 more
europepmc   +1 more source

Islamic Calvinists : Change and conservatism in Central Anatolia / European Stability Initiative

, 2005
unknown
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Four decades of genomic stability and adaptive divergence in <i>Xanthomonas</i> phages: defining <i>Duraznoxanthovirus arenicola</i> and its evolutionary framework. [PDF]

Front Microbiol
D'Amico-Willman KM, Joglekar P, Turner D, Flaherty M, Ritchie DF, Huerta AI.   +5 more
europepmc   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Lysine demethylase 4A is a centrosome-associated protein required for centrosome integrity and genomic stability. [PDF]

FEBS J
Chowdhury P, Wang X, Han RI, Motrapu M, Boice AG, Nakatani Y, Vargas-Hernandez S, Love JF, Chew C, Grimm SL, Mezquita D, Mason FM, Martinez ED, Coarfa C, Walker CL, Gustavsson AK, Dere R.   +16 more
europepmc   +1 more source