Results 171 to 180 of about 833,584 (297)

Genetic data normalization for genomic medicine: a Fast Healthcare Interoperability Resources Genomics reference implementation. [PDF]

J Am Med Inform Assoc
Dolin RH, Todor NM, Shalaby J, Arsalan H, Shah E, Basravi N, Husami A, Rampersad A, Heale BSE, Chamala S.   +9 more
europepmc   +1 more source

Purification of genomic sequences from bacteriophage libraries by recombination and selectionin vivo [PDF]

, 1983
Brian Seed
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Safe and effective genomic medicine implementation in hospitals: a scoping review. [PDF]

BMJ Open Qual
Clucas L, Kelly C, Do TT, Beadell I, Dawson-McClaren B, Gaff CL.   +5 more
europepmc   +1 more source

Rat glycine methyltransferase. Complete amino acid sequence deduced from a cDNA clone and characterization of the genomic DNA [PDF]

, 1987
Hirofumi Ogawa, Kiyoshi Konishi, Yoshimi Takata, Hiroshi Nakashima, Motoji Fujioka   +4 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Editorial: Accelerating cancer genomics research in Sub-Saharan Africa. [PDF]

Front Oncol
Odedina FT, Rotimi SO, Zoure AA.
europepmc   +1 more source

Structure of the Mouse Cytochrome P₁‐450 Genomic Gene [PDF]

, 1983
Michitoshi Nakamura, Masahiko Negishi, Mario Altieri, Yuan‐Tsong Chen, Toshihiko Ikeda, Robert H. Tukey, Daniel W. Nebert   +6 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Decoding the mystery: AI-assisted bioinformatics and functional genomics technologies in medicinal plants. [PDF]

Front Plant Sci
Song C, Sabir IA, Zhao W, Cao Y.
europepmc   +1 more source