Results 191 to 200 of about 860,476 (247)

EWAS Open Platform 2026: a deeply integrated resource for epigenome-wide association studies. [PDF]

Nucleic Acids Res
Yang F, Xiong Z, Zong W, Kong D, Tang B, Chen X, Wei Y, Yu X, Zhang Y, Zou D, Zhang Z, Bao Y, Li R.   +12 more
europepmc   +1 more source

Genomic features and evolution of the conditionally dispensable chromosome in the tangerine pathotype of Alternaria alternata

, 2019
Mingshuang Wang, Huilan Fu, Xing‐Xing Shen, Ruoxin Ruan, Antonis Rokas, Hongye Li   +5 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Correction: PAHG: the database of human multi-gene families. [PDF]

BMC Genom Data
Azhar R, Malik MF, Arif R, Khokhar MW, Abbasi YM, Batool F, Jalalzai MH, Bao Y, Abbasi AA.   +8 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Construction of an integrated database to support genomic sequence analysis

, 1999
Patrick M. Gillevet, Ross Overbeek
openalex   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Computational Analysis of Genomic Regions of Human Insulin Receptor Gene

, 2016
Shahid Raza, Hira Mubeen
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

MoGAAAP: a modular Snakemake workflow for automated genome assembly and annotation with quality assessment. [PDF]

NAR Genom Bioinform
van Workum DM, Dey KK, Kozik A, Lavelle DO, de Ridder D, Schranz ME, Michelmore RW, Smit S.   +7 more
europepmc   +1 more source