Results 171 to 180 of about 1,577,423 (359)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

2023 International Workshop on Environmental Genomics: New horizons for environmental genomics applications

open access: yes
A summary report of the 8th annual International Workshop on Environmental Genomics (IWEG)
Centre for Environmental Genomics Applications, CEGA
core   +1 more source

Peach structural genomics

open access: yes, 2009
Peach (Prunus persica) belongs to the Prunus genus and is a member of the Rosaceae family. It has been selected as a model species for genomics studies in virtue of several features (Abbott et al., 2002): it has a short juvenile phase (2–3 years) if ...
Carlo Pozzi   +3 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Marine Population Genomics: Challenges and Opportunities

open access: yes, 2019
Population genomics is revolutionizing biology and stimulating new research questions and directions. While human health has driven many of the genomics tools and approaches, all other biological fields have benefitted.
Marjorie F. Oleksiak   +3 more
core   +1 more source

A long road ahead to reliable and complete medicinal plant genomes

open access: yesNature Communications
Long-read DNA sequencing has propelled medicinal plant genomics forward, with over 400 genomes from 203 plants sequenced by February 2025. However, many genomes still have assembly and annotation flaws, with only 11 gapless telomere-to-telomere ...
Ling-Tong Cheng   +4 more
doaj   +1 more source

The Signal in the Genomes

open access: yesPLoS Computational Biology, 2006
Nostra culpa. Not only did we foist a hastily conceived and incorrectly executed simulation on an overworked RECOMB conference program committee, but worse—nostra maxima culpa—we obliged a team of high-powered researchers to clean up after us! It was never our intention to introduce an alternative way of constructing synteny blocks; the so-called ST ...
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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