Results 201 to 210 of about 860,476 (247)
Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose +11 morewiley +1 more sourcegenomic coordinates of the mouse CAGE peaks
, 2017 Hans Clevers, Albert S.B. Edge, Marc van de Wetering, Michael Detmar, Haruhiko Koseki, Matthias Edinger, Karl Ekwall, David Hume, Richard A Axton, Mitsuko Hara, Toshio Kitamura, Yuki Hasegawa, Naoko Takahashi, Piero Carninci, Ernst J. Wolvetang, Dmitry Ovchinnikov, Carrie Davis, Hideya Kawaji, T Gingeras, Hiroshi Tanaka, Lesley M. Forrester, Daisuke Sugiyama, Geoffrey J. Faulkner, Valerio Orlando, Masayoshi Itoh, Alan Mackay‐Sim, Masayuki Yamamoto, Teunis B. H. Geijtenbeek, Peter Arner, Juha Kere, Alistair R. R. Forrest, Antti Sajantila, Robert Passier, Andreas Lennartsson, Christine L. Mummery, Ana Pombo, Jun Kawai, James Briggs, Sachi Kato, Harukazu Suzuki, Yoshihide Hayashizaki, Takeya Kasukawa, Timo Lassmann, Jay W. Shin, Hideki Tatsukawa, Peter Arner, Anna Ehrlund, Niklas Mejhert, Tim Barnett, Hozumi Mothashi, Levon M. Khachigian, Judith S. Kempfle, Chieko Kai, Misako Yoneda, Hiroki Sato, Reto Guler, Magda Babina, Tony Kenna, Beatrice Bodega, Soichi Kojima, Mariko Okada, Yasushi Okazaki, Michela Faglioni, Masaaki Furuno, S. Zucchelli, Christine A. Wells, Kim Summers, Mitsuru Morimoto, Patrizia Rizzu, Mitsuhiro Ohshima, Yoko Yamaguchi, Marina Lizio, Taeko Dohi, Guojun Sheng, Imad Abugessaisa, Dan Goldowitz, Peter Heutink, Alka Saxena, S. Noguchi, Mizuho Ohno, Shoko Watanabe, Akira Hasegawa, Jessica Severin, Jayson Harshbarger, Xian‐Yang Qin, Takahiro Arakawa, Shiro Fukuda, Fumi Hori, Kaoru Kaida, Ai Kaiho, Mutsumi Kanamori-Katayama, Tsugumi Kawashima, Miki Kojima, Atsutaka Kubosaki, Ri‐Ichiroh Manabe, Mitsuyoshi Murata, Sayaka Nagao-Sato, Noriko Ninomiya, Hiromi Nishiyori-Sueki, Shohei Noma +99 moreopenalex +1 more sourceMicroglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling +6 morewiley +1 more sourceNuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome +5 morewiley +1 more sourceThe UCSC Genome Browser database: 2026 update. [PDF]
Nucleic Acids ResCasper J, Speir ML, Raney BJ, Perez G, Nassar LR, Lee CM, Hinrichs AS, Gonzalez JN, Fischer C, Diekhans M, Clawson H, Benet-Pages A, Barber GP, Vaske CJ, van Baren MJ, Wang K, Rodriguez YJP, Jenkins-Kiefer JA, Chalamala M, Haussler D, Kent WJ, Haeussler M. +21 moreeuropepmc +1 more sourceIntegrated genomic analysis to reduce chromosomal analysis for the diagnosis of pediatric hematologic malignancies: addressing the shortage of cytogenetic technologists
Dong Li, Sarah K. Tasian, Gerald Wertheim, Susan R. Rheingold, Kathrin M. Bernt, Haley Newman, Luanne Wainwright, Donna Wilmoth, Brian Thiel, Lea F. Surrey, Elizabeth Margolskee, Vinodh Pillai, Minjie Luo, Michele Paessler, Stephen P. Hunger, Marilyn M. Li, Yiming Zhong +16 moreopenalex +1 more sourceThe Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention. Hanqing He, Jianwei Wangwiley +1 more source
