Results 201 to 210 of about 1,946,862 (417)

Efficient and Scalable Fine-Tune of Language Models for Genome Understanding [PDF]

arXiv
Although DNA foundation models have advanced the understanding of genomes, they still face significant challenges in the limited scale and diversity of genomic data. This limitation starkly contrasts with the success of natural language foundation models, which thrive on substantially larger scales.
arxiv  

Cloning and analysis of a genomic fragment of Dictyostelium discoideum hybridizing to an RNA specifically accumulated in spore cells [PDF]

, 1982
Jacqueline Julien, Jacques Camonis, Michel Jacquet   +2 more
openalex   +1 more source

The Ectocarpus Genome and Brown Algal Genomics

, 2012
Brown algae are important organisms both because of their key ecological roles in coastal ecosystems and because of the remarkable biological features that they have acquired during their unusual evolutionary history. The recent sequencing of the complete genome of the filamentous brown alga Ectocarpus has provided unprecedented access to the molecular
Colin Brownlee, Betsy A. Read, Hiroshi Kawai, Stefan A. Rensing, Sylvie Doulbeau, Patrick Wincker, Bank Beszteri, Bank Beszteri, Florian Maumus, Chris Bowler, Martina Strittmatter, John H. Bothwell, John H. Bothwell, John H. Bothwell, Taizo Motomura, Véronique Anthouard, Pascal J. Lopez, Thierry Tonon, Thierry Tonon, Martin Lohr, Erwan Corre, Carolyn A. Napoli, Catherine Leblanc, Catherine Leblanc, Olivier Godfroy, Olivier Godfroy, Takahiro Yamagishi, Claire Jubin, Corinne Da Silva, Alok Arun, Alok Arun, Hadi Quesneville, Simon M. Dittami, Simon M. Dittami, Julie Poulain, Akira F. Peters, Akira F. Peters, Eric Bonnet, Eric Bonnet, Julia Morales, Julia Morales, Grigoris D. Amoutzias, Grigoris D. Amoutzias, Hervé Moreau, Philippe Potin, Philippe Potin, Remy Luthringer, Remy Luthringer, James W. Tregear, Cindy Martens, Daniel Lang, Claire M. M. Gachon, Gurvan Michel, Gurvan Michel, J. Mark Cock, J. Mark Cock, Garry Farnham, Jonathan H. Badger, Svenja Heesch, Svenja Heesch, Sophia Ahmed, Sophia Ahmed, Pierre Rouzé, Ga Youn Cho, Ga Youn Cho, Marek Eliáš, Laurence Dartevelle, Laurence Dartevelle, Peter von Dassow, Patrice Lerouge, Nicolas Macaisne, Nicolas Macaisne, Yves Van de Peer, David R. Nelson, Carl J. Carrano, Ludovic Delage, Ludovic Delage, Frithjof C. Küpper, Frithjof C. Küpper, François Artiguenave, Delphine Scornet, Delphine Scornet, Andrés Ritter, Andrés Ritter, Andrés Ritter, Manoj P. Samanta, Bénédicte Charrier, Bénédicte Charrier, Kamel Jabbari, Chikako Nagasato, Jean-Marc Aury, Klaus Valentin, Bernard Kloareg, Bernard Kloareg, Pi Nyvall-Collén, Pi Nyvall-Collén, Gaelle Samson, Catherine Boyen, Catherine Boyen, Gildas Le Corguillé, Bernhard Gschloessl, Bernhard Gschloessl, Diego Miranda-Saavedra, Kenny Billiau, Nicolas Delaroque, Jonas Collén, Jonas Collén, Andrew E. Allen, Susana M. Coelho, Susana M. Coelho, Declan C. Schroeder, Béatrice Segurens, Aude Le Bail, Aude Le Bail, Kei Kimura, Lieven Sterck, Sylvie Rousvoal, Sylvie Rousvoal, Cyril Pommier   +118 more
openaire   +5 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen, Meng‐Meng Ji, Peng‐Peng Xu, Wei‐Li Zhao   +3 more
wiley   +1 more source

Genomic Footprinting of a Yeast tRNA Gene Reveals Stable Complexes over the 5′-Flanking Region [PDF]

, 1989
Jon M. Huibregtse, David R. Engelke
openalex   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Functional Genomics and Comparative Genomics Analysis in Plants

Current Issues in Molecular Biology
The study of plant genomics has significantly deepened our understanding of plant evolution and adaptation from a microscopic perspective [...]
Yueqi Lu, Quan Zou
doaj   +1 more source

MicroRNAs Genomics, Biogenesis, Mechanism, and Function

Cell, 2004
D. Bartel
semanticscholar   +1 more source

Human beta satellite DNA: genomic organization and sequence definition of a class of highly repetitive tandem DNA. [PDF]

, 1989
John S. Waye, H F Willard
openalex   +1 more source