Results 301 to 310 of about 1,946,862 (417)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

SpectroPipeR-a streamlining post Spectronaut® DIA-MS data analysis R package. [PDF]

Bioinformatics
Michalik S, Hammer E, Steil L, Salazar MG, Hentschker C, Surmann K, Busch LM, Sura T, Völker U.   +8 more
europepmc   +1 more source

Genomic organization of alpha satellite DNA on human chromosome 7: evidence for two distinct alphoid domains on a single chromosome.

, 1987
John S. Waye, Sarah England, H F Willard
openalex   +1 more source

Genomic hypomethylation and far-5' sequence alterations are associated with carcinogen-induced activation of the hamster thymidine kinase gene. [PDF]

, 1986
Frederic G. Barr, S. Rajagopalan, Craig A. MacArthur, Michael W. Lieberman   +3 more
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Use of RecA protein to enrich for homologous genes in a genomic library [PDF]

, 1988
Behnaz Taidi‐Laskowski, Dolly B. Tyan, Saul M. Honigberg, Charles R. Radding, F. Carl Grumet   +4 more
openalex   +1 more source

Genomics [PDF]

Plant Physiology, 1998
openaire   +2 more sources

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Correction: Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes. [PDF]

BMC Genomics
Gibbs DC, McCrary MR, Moreno CS, Seldin L, Li C, Kamili NAH, Pollack BP.   +6 more
europepmc   +1 more source

Population genomics of Bronze Age Eurasia

Nature, 2015
M. Allentoft, M. Sikora, K. Sjögren, Simon Rasmussen, M. Rasmussen, Jesper T. Stenderup, P. B. Damgaard, Hannes Schroeder, Torbjörn Ahlström, L. Vinner, Anna-Sapfo Malaspinas, A. Margaryan, Tom Higham, D. Chivall, N. Lynnerup, L. Harvig, J. Baron, P. D. Casa, P. Dąbrowski, Paul R. Duffy, Alexander V. Ebel, A. Epimakhov, K. Frei, M. Furmanek, Tomasz Gralak, A. Gromov, S. Gronkiewicz, G. Grupe, Tamás Hajdu, Radosław Jarysz, V. Khartanovich, A. Khokhlov, V. Kiss, J. Kolář, A. Kriiska, Irena Lasak, C. Longhi, George C. McGlynn, A. Merkevičius, Inga Merkytė, M. Metspalu, R. Mkrtchyan, V. Moiseyev, László Paja, G. Pálfi, Dalia Pokutta, Łukasz Pospieszny, T. D. Price, Lehti Saag, M. Sablin, N. Shishlina, V. Smrcka, V. Soenov, Vajk Szeverényi, Gusztáv Tóth, S. Trifanova, Liivi Varul, M. Vicze, L. Yepiskoposyan, V. Zhitenev, L. Orlando, Thomas Sicheritz-Pontén, S. Brunak, R. Nielsen, K. Kristiansen, E. Willerslev   +65 more
semanticscholar   +1 more source