Results 161 to 170 of about 2,216,855 (328)

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Genotype-Environment Interactions in Egg Production Stocks of Chickens

, 1969
H.L. MARKS, C.H. Moore, N.R. Gyles, H.R. Wilson, L.D. Tindell, William A. Johnson, L.J. Dreesen, W.L. Blow, W.F. Krueger, P.B. Siegel   +9 more
openalex   +1 more source

Differences in competitive ability between genotypes of Drosophila [PDF]

, 1962
Kenneth Mather, Patricia Cooke
openalex   +1 more source

Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean

Advanced Science, EarlyView.
This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang, Xinyu Jiang, Xiaobo Yuan, Zhipeng Zhou, Zhenwei Zhao, Longfei Wang, Wu Jiao, Wenxue Ye, Qingxin Song   +8 more
wiley   +1 more source

Characterization of genetic mutations in hepatitis B virus isolated from HBsAg+/HBcAb+/HBsAb-/HBV DNA + Japanese blood donors. [PDF]

Sci Rep
Sedohara A, Takahashi K, Tsutsumi T, Arai K, Nakahara F, Ikeuchi K, Adachi E, Yotsuyanagi H.   +7 more
europepmc   +1 more source

Genotype-Environment Interactions in Broiler Stocks of Chickens

, 1969
H.L. MARKS, C.H. Moore, N.R. Gyles, L.D. Tindell, William A. Johnson, L.J. Dreesen, W.L. Blow, Gerald A. Martin, W.F. Krueger, P.B. Siegel   +9 more
openalex   +1 more source

The Effect of Plethora on Growth and Differentiation of Normal Hemopoietic Colony-Forming Cells Transplanted in Mice of Genotype W/Wv [PDF]

, 1967
J. E. Till, Louis Siminovitch, E. A. McCulloch   +2 more
openalex   +1 more source

Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

Proceedings of the National Academy of Sciences of the United States of America, 2001
M. Egan, T. Goldberg, B. Kolachana, J. Callicott, C. Mazzanti, R. Straub, D. Goldman, D. Weinberger   +7 more
semanticscholar   +1 more source

Reprogramming of Fatty Acid Metabolism via PPARα‐Orchestrated FADS2 in Keratinocytes Modulates Skin Inflammation in Psoriasis

Advanced Science, EarlyView.
This study identifies fatty acid desaturase 2 (FADS2) as a key regulator linking polyunsaturated fatty acid (PUFA) metabolism to psoriatic inflammation. FADS2 deficiency impairs docosahexaenoic acid (DHA) biosynthesis, enhances NF‐κB signaling, and promotes neutrophil‐driven skin inflammation. PPARα transcriptionally activates FADS2, and its activation
Jiangluyi Cai, Xue Zhou, Yu Zhuang, Lian Cui, Rui Ma, Youdong Chen, Nan Yang, Qianyu Chen, Yuanyuan Wang, Peiyao Zhu, Lingling Yao, Qian Yu, Xiaomin She, Xuyang Zhou, Yuemeng Huang, Zengyang Yu, Xilin Zhang, Jiajing Lu, Yuling Shi, Chunyuan Guo   +19 more
wiley   +1 more source

Thermal processing and geographical origin as drivers of terpenoids variation in Anethum graveolens L. essential oils: A biplot analysis. [PDF]

PLoS One
Farmanpour Kalalagh K, Mohebodini M, Sabaghnia N, Beyraghdar Kashkooli A, Esmaeili H.   +4 more
europepmc   +1 more source